国际妇产科学杂志 ›› 2015, Vol. 42 ›› Issue (4): 417-420.

• 综述 • 上一篇    下一篇

薄型子宫内膜的临床处理进展

郭欢欢,孙蓬明,林元   

  1. 350001 福建省福州市,福建省妇幼保健院 福建医科大学教学医院
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2015-08-15 发布日期:2015-08-15
  • 通讯作者: 林元

The Development of Therapy of Thin Endometrium

GUO Huan-huan,SUN Peng-ming,LIN Yuan   

  1. Fujian Provincial Maternal and Children Health Hospital,Fujian Medical University Teaching Hospital,Fuzhou 350001,China
  • Received:1900-01-01 Revised:1900-01-01 Published:2015-08-15 Online:2015-08-15
  • Contact: LIN Yuan

摘要: 有着床能力的胚胎、容受性良好的子宫内膜以及胚胎和母体的相互作用是胚胎成功种植的主要因素。子宫内膜厚度仍是目前临床评价子宫内膜容受性的重要指标。月经周期中子宫内膜厚度可以反映内膜功能状态,子宫内膜充分的增殖和向分泌期转化是胚胎成功着床的前提条件之一。目前一致认为,薄型子宫内膜显著降低胚胎种植率,此外,薄型子宫内膜也是导致女性不孕的重要原因之一。因此,探索薄型子宫内膜的病因并积极治疗、提高子宫内膜的容受性非常重要。对妨碍胚胎种植的子宫内膜进行预处理,通过治疗使子宫内膜增加至正常厚度,将有助于提高妊娠率及活产率。然而,目前薄型子宫内膜的治疗方法大多效果不理想。综述薄型子宫内膜的定义、病因及临床处理研究进展。

关键词: 子宫内膜, 生殖技术, 辅助, 受精, 体外, 胚胎移植, 治疗学, 综述

Abstract: The main factors of successful implantation of embryo include the ability to bed, the good receptive endometrium, the interaction of embryo and maternal. Endometrial thickness has been evaluated as a possible predictor of endometrial receptivity. Endometrial thickness in menstrual cycle can reflect the state of endometrial function. Adequate proliferation and secretory changes during the luteal phase is considered to be one of the prerequisites for successful implantation of the embryo. Reports have shown that a thin endometrium is closely associated with lower implantation rates. Furthermore, thin endometrium is an important cause of female infertility. It is important to look for the etiology, active treatment, and improve the endometrium receptivity. Pretreatment to the thin endometrium and increasing endometrial thickness to normal condition will help to improve the rates of pregnancy and live birth. However, the treatments of thin endometrium are not ideal at present. In this paper,we will review the definition,etiology and clinical treatment of thin endometrium.

Key words: Endometrium, Reproductive techniques, assisted, Fertilization in vitro, Embryo transfer, Therapeutics