国际妇产科学杂志

国际妇产科学杂志 ›› 2010, Vol. 37 ›› Issue (2): 139-141.

• 论著 • 上一篇    下一篇

持续性异位妊娠最佳治疗方法的研究

李环,张礼婕,李蓉,张媛,钟凯,孙红梅,吴瑞芳   

  1. 518036 深圳,北京大学深圳医院妇产科
  • 收稿日期:2009-08-03 修回日期:1900-01-01 出版日期:2010-04-15 发布日期:2010-04-15

Clinical Study of the Efficacy Therapy for Persistent Ectopic Pregnancy

LI Huan, ZHANG Li-jie, LI Rong, ZHANG Yuan, ZHONG Kai, SUN Hong-mei, WU Rui-fang   

  1. Department of Obstetrics and Gynecology, Beijing University Shenzhen Hospital, Shenzhen 518036, China
  • Received:2009-08-03 Revised:1900-01-01 Published:2010-04-15 Online:2010-04-15

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摘要： 目的：探讨持续性异位妊娠（PEP）的最佳治疗方法。方法：对155例PEP患者随机采用3种不同治疗方法：A组期待疗法；B组甲氨蝶呤（MTX）局部注射治疗；C组MTX加米非司酮全身用药。对3组治疗成功率、失败率、不良反应、治疗时间和产生的费用进行观察分析研究。结果：B组成功率最高，A组失败率最高；C组不良反应最强，B组不良反应最低；A组治疗时间最长，C组治疗时间最短，3组在治疗时间上差异无统计学意义；C组产生的费用最多，B组的费用最低。结论：PEP后有多种治疗方法，其中，经阴道局部注射MTX治疗是最佳的选择。

关键词: 持续性异位妊娠, 期待疗法, 局部注射治疗, 全身用药治疗, 甲氨蝶呤

Abstract: Objective: To investigate the efficacy therapy for persistent ectopic pregnancy（PEP）. Methods: 155 patients with persistent ectopic pregnancy were randomly divided into 3 treatment groups: Group A received expectant treatment, Group B received methotrexate local injection treatment, and Group C received systemic administration mifepristone and methotrexate. Successful rate, failure rate, adverse reaction, treatment time and treatment cost of each groups were analyzed and compared. Results: The successful rate of Group B is highest. The failure rate of Group A is highest. The side effect in Group C is strongest, less side effect in Group B. Longer treatment time in Group A, shorter treatment time in Group C, there is no statistical differences in the time of 3 groups. The cost of Group C is highest, and Group B is lowest if the treatment is successful. Conclusions: There are a lots of treatment for persistent ectopic pregnancy, Methotrexate local injection treatment is the best therapy for persistent ectopic pregnancy.

Key words: Persistent ectopic pregnancy, Expectant treatment, Local injection treatment, Systemic administration, Methotrexate