国际妇产科学杂志

国际妇产科学杂志 ›› 2013, Vol. 40 ›› Issue (3): 241-243.

• 综述 • 上一篇    下一篇

甲苯胺蓝染色在诊断子宫内膜病变中的研究进展

崔淑敏, 孔宪超   

  1. 150001 哈尔滨医科大学（崔淑敏）；哈尔滨医科大学附属第二医院妇产科（孔宪超）
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2013-06-15 发布日期:2013-06-15
  • 通讯作者: 孔宪超

Research Progress in Toluidine Blue Staining in the Diagnosis of Endometrial Pathologies

CUI Shu-min，KONG Xian-chao   

  1. Harbin Medical University，Harbin 150001，China（CUI Shu-min）；The Second Affiliated Hospital of Harbin Medical University，Harbin 150001，China（KONG Xian-chao）
  • Received:1900-01-01 Revised:1900-01-01 Published:2013-06-15 Online:2013-06-15
  • Contact: KONG Xian-chao

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摘要： 甲苯胺蓝（toluidine blue，TB）是用于核酸染色的重要染色剂，可用于检测临床上可能忽视的某些癌前病变或癌症。20世纪80年代以来，TB染色法被广泛应用于口腔、外阴及上消化道恶性肿瘤的诊断。随着科技的发展，TB染色对子宫内膜病变检查的优势已逐渐引起国内外专家的重视，由于技术和设备等因素限制，其在子宫内膜癌及其癌前病变的研究尚处于初级阶段，综述TB染色法在子宫内膜癌及其癌前病变的研究进展。

关键词: 染色与标记, 子宫内膜肿瘤, 癌前状态, 宫腔镜, 诊断

Abstract: Toluidine blue（TB）is a vital dye used for nucleic acid staining. We can use the staining for detection of the early malignant or premalignant endometrium lesions. Since the 1980s，TB staining has been used in the investigation of oral，vulvar，and upper gastrointestinal tract malignancies. With the development of science and technology，advantages of TB staining in endometrial pathological diagnosis has gradually aroused great attention from domestic and foreign experts，however，due to the limit of techniques，equipment and many other factors，the research of the TB staining in endometrial cancer and endometrial precancer is still at its initial stage.Based on the above，this paper reviews the research progress of toluidine blue staining in the diagnosis of endometrial carcinoma and precancerous lesions.

Key words: Staining and labeling, Endometrial neoplasms, Precancerous conditions, Hysteroscopes, Diagnosis