国际妇产科学杂志

国际妇产科学杂志 ›› 2015, Vol. 42 ›› Issue (2): 177-179.

• 综述 • 上一篇    下一篇

花生四烯酸及其代谢产物与围绝经期的关系

周之伟，王文娟，白文佩，秦丽华   

  1. 100191 北京大学医学部基础医学院解剖学与组织胚胎学系（周之伟，王文娟，秦丽华）；北京大学第一医院（白文佩）
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2015-04-15 发布日期:2015-04-15
  • 通讯作者: 秦丽华

Arachidonic Acid and Its Metabolites with Perimenopause

ZHOU Zhi-wei，WANG Wen-juan，BAI Wen-pei，QIN Li-hua   

  1. Department of Anatomy and Embryology，School of Basic Medicine，Peking University Health Science Center，Beijing 100191，China（ZHOU Zhi-wei，WANG Wen-juan，QIN Li-hua）； Department of Obstetrics and Gynecology，Peking University First Hospital，Beijing 100034，China（BAI Wen-pei）
  • Received:1900-01-01 Revised:1900-01-01 Published:2015-04-15 Online:2015-04-15
  • Contact: QIN Li-hua

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5419

被引次数

1

摘要： 花生四烯酸是人体必需的游离脂肪酸之一，花生四烯酸及其产物在调节人体炎症反应、血管弹性、白细胞功能、骨的重塑和血小板活化中具有重要作用。新近研究发现，花生四烯酸在绝经后女性血液中的含量会发生变化，花生四烯酸及其产物与绝经后高血压、肥胖和骨质疏松等疾病有关。此外，饮食因素对绝经后血液花生四烯酸的调节起重要作用。就围绝经期前后花生四烯酸的含量变化及其可能机制和绝经后妇女饮食与体内花生四烯酸变化的关系进行综述。

关键词: 花生四烯酸, 围绝经期, 饮食习惯

Abstract: Arachidonic acid is one of the essential free fatty acids. Arachidonic acid and its products play an important role in regulating the body inflammation, blood vessels, elastic, leukocyte function, bone remodeling and platelet activation. Recent studies have found that arachidonic acid levels in the blood may change after menopause. Arachidonic acid and its product are related with postmenopausal hypertension, obesity, osteoporosis, etc. Moreover, after menopause, dietary factors can regulate the content of blood arachidonic acid. In this paper, before and after menopausal transition to the variation in content of arachidonic acid and its possible mechanism and postmenopausal women the relationship between diet and arachidonic acid in the body change were summarized.

Key words: Arachidonic acid, Perimenopause, Food habits