国际妇产科学杂志

国际妇产科学杂志 ›› 2016, Vol. 43 ›› Issue (3): 254-257.

• 综述 • 上一篇    下一篇

雌激素在围手术期辅助治疗宫腔粘连的研究进展

陈熹婷，陈勍，刘畅浩，黄妙玲，管媚媚   

  1. 510120 广州，中山大学孙逸仙纪念医院妇瘤科
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2016-06-22 发布日期:2016-06-22
  • 通讯作者: 陈勍

Advances of Perioperative Estrogen Therapy in Patients with Intrauterine Adhesions

CHEN Xi-ting, CHEN Qing, LIU Chang-hao, HUANG Miao-ling, GUAN Mei-mei   

  1. Department of Gynecology Oncology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou 510120, China
  • Received:1900-01-01 Revised:1900-01-01 Published:2016-06-22 Online:2016-06-22
  • Contact: CHEN Qing,

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摘要： 随着宫腔操作的增加及宫腔镜手术的普及，宫腔粘连发病率逐年增加。目前，宫腔粘连分离术是治疗宫腔粘连患者的有效手段，雌激素作为围手术期的辅助治疗方法被广泛用于临床，但是雌激素治疗仍以经验性治疗为主。本文主要通过复习近期相关文献，了解宫腔粘连时子宫内膜的变化，深入探究雌激素治疗宫腔粘连的作用机制、有效性，并总结雌激素在围手术期治疗宫腔粘连的用药剂量、时间、模式等治疗策略，为围手术期宫腔粘连患者的雌激素治疗方案提供依据。

关键词: 子宫疾病, 黏连, 雌激素类, 宫腔镜, 宫腔镜检查, 子宫内膜

Abstract: Recently, with the popularity of intrauterine operation, the incidence of intrauterine adhesions(IUA) is increasing gradually. Hysteroscopic adhesiolysis has become an effective treatment of IUA. Estrogen use as an perioperative adjuvant therapy has been extensively applied to clinical practice，however the treatment remains empirically based. The purpose of this article was to review the literature to understand changes of endometrium with intrauterine adhesions and to analyze the mechanism and efficacy of estrogen therapy. Furthermore, this article summarized the dose,duration and other treatment strategies of estrogｅｎ，ｗhich provide evidence to use estrogen as perioperative adjuvant therapy in IUA.

Key words: Uterine diseases, Adhesions, Estrogens, Hysteroscopes, Hysteroscopy, Endometrium