国际妇产科学杂志

国际妇产科学杂志 ›› 2017, Vol. 44 ›› Issue (5): 529-532.

• 论著 • 上一篇    下一篇

卵巢交界性肿瘤保留生育功能的手术途径选择

赵建国，刘彩艳，刘静，何萍，曲芃芃，徐欣然   

  1. 300100  天津市中心妇产科医院妇瘤科
  • 收稿日期:2017-06-16 修回日期:2017-08-28 出版日期:2017-10-15 发布日期:2017-10-25
  • 通讯作者: 曲芃芃，E-mail：qu.pengpeng@hotmail.com E-mail:qu.pengpeng@hotmail.com
  • 基金资助:
    天津市卫生局科技基金（2015KZ078）

Selection of Surgical Approaches for Sparing-fertility in Borderline Ovarian Tumors

ZHAO Jian-guo，LIU Cai-yan，LIU Jing，HE Ping，QU Peng-peng，XU Xin-ran   

  1. Department of Gynecological Oncology，Tianjin Central Hospital of Gynecology Obstetrics，Tianjin 300100，China
  • Received:2017-06-16 Revised:2017-08-28 Published:2017-10-15 Online:2017-10-25
  • Contact: QU Peng-peng，E-mail：qu.pengpeng@hotmail.com E-mail:qu.pengpeng@hotmail.com

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摘要： 目的：研究卵巢交界性肿瘤行腹腔镜或开腹保留生育功能手术对短期预后及妊娠的影响。方法：收集天津市中心妇产科医院2009年1月—2015年7月卵巢交界性肿瘤行保留生育功能手术患者共74例，其中开腹组30例，腹腔镜组44例。比较2组患者复发及妊娠情况。结果：开腹组较腹腔镜组年轻（P=0.018）、开腹组肿瘤最大径线超过腹腔镜组（P=0.000），腹腔镜组中未分期手术患者较开腹组多（P=0.000）。术后总复发率为6.7%（5/74），2组复发率比较差异无统计学意义（P=0.980）。保留生育功能术后患者总妊娠率为33.8%（25/74），其中开腹组为30.0%（9/30），腹腔镜组为36.4%（16/44），2组间比较差异无统计学意义（P=0.570）；腹腔镜组未分期手术妊娠患者比例高于开腹组（P=0.041），其中术后妊娠患者中无复发。结论：腹腔镜保留生育功能的未分期手术短期预后及术后妊娠情况满意，对卵巢交界性肿瘤患者选择性行腹腔镜保留生育功能的未分期手术是安全可行的。

关键词:  卵巢交界性肿瘤, 保留生育功能手术, 腹腔镜, 预后, 妊娠

Abstract: Objective：To research short-outcome and effect on pregnancy after sparing-fertility surgery of the borderline ovarian tumors (BOTs) with laparoscopy or laparotomy approach. Methods：Clinic-pathologic variants of 74 sparing-fertility cases with BOTs from January 2009 to July 2015 in the Tianjin Central Hospital of Obstetrics & Gynecology were analyzed retrospectively. 44 cases and 30 cases were carried out laparoscopic surgery and laparotomy surgery respectively. Recurrence and pregnancy of two groups were compared. Results：Age of laparotomy group was younger than that of laparoscopic group significantly (P=0.018). Maximal longitude of tumor in laparotomy group was significantly longer than that of the laparoscopic group (P=0.000). Number of unstaging cases in laparoscopic group were significantly more than that of laparotomy group (P=0.000). Total recurrent rate was 6.7% (5/74). There were no significant differences of recurrent rate between the two groups (P=0.980). The total pregnant rate was 33.8% (25/74) in sparing-fertility patients, 30% (9/30) in laparotomic group, 36.4% (16/44) in the laparoscopic group with insignificant difference between two groups (P=0.570). The pregnancy rate of unstaging cases in laparoscopic group was significantly higher than that of laparotomy group (P=0.041). No recurrence occurred in pregnant cases. Conclusions：Short-outcome and pregnancy of BOTs patients with unstaging laparoscopic sparing-fertility surgery were satisfactory. It was safe and feasible to undergo laparoscopic sparing-fertility surgery in selectable patients with BOTs.

Key words: Borderline ovarian tumors, Sparing-fertility surgery, Laparoscopy, Prognosis, Pregnancy