国际妇产科学杂志 ›› 2019, Vol. 46 ›› Issue (6): 609-613.

• 综述 • 上一篇    下一篇

磁共振弥散张量成像在子宫及子宫疾病中的应用研究进展

张文婷*,尹化斌   

  1. 200240 上海,复旦大学附属上海市第五人民医院放射科
  • 收稿日期:2019-04-25 修回日期:2019-06-26 出版日期:2019-12-15 发布日期:2019-12-15
  • 通讯作者: 尹化斌,E-mail:hbyin1961@126.com E-mail:hbyin1961@126.com
  • 基金资助:
    上海市第五人民医院放射科院级重点专科项目(2017WYZDZK13)

Research Progress on the Application of Diffusion Tensor Imaging in Uterus and Uterine Diseases

ZHANG Wen-ting,YIN Hua-bin   

  1. Department of Radiology,The Fifth People′s Hospital of Shanghai,Fudan University,Shanghai 200240,China
  • Received:2019-04-25 Revised:2019-06-26 Published:2019-12-15 Online:2019-12-15
  • Contact: YIN Hua-bin,E-mail:hbyin1961@126.com E-mail:hbyin1961@126.com
  • Supported by:
     

摘要: 磁共振弥散张量成像(DTI)通过量化人体组织中水分子的弥散速度和方向,反映组织的微观结构及生理、病理内环境的改变,其相关参数部分各向异性分数(FA)、表观弥散系数(ADC)可提供更多微观、定量信息。纤维示踪成像(FT)可直观显示纤维束的方向和分布情况,无创地显示更多的解剖细节。目前DTI在子宫中的应用研究逐步受到关注,其可良好地显示正常子宫的纤维结构并应用于子宫疾病中,例如普通子宫肌瘤与变性肌瘤的区分及超声消融术后疗效评价,子宫内膜癌和宫颈癌术前分期、淋巴结转移的判定及预后评估,对骶神经根显微结构的显示以反映子宫内膜异位症的病理生理改变等,为临床提供更多的信息,有助于临床诊断和后续治疗方案的选择及预后评估。

关键词: 子宫, 子宫疾病, 磁共振成像, 弥散张量成像, 各向异性

Abstract: Diffusion tensor imaging (DTI) is able to quantify the velocity and direction of water molecules in human tissues, thus to reflect micro-structure of tissues as well as physiological and pathological changes. DTI related parameters fractional anisotropy (FA) and apparent diffusion coefficient (ADC) value can reveal microscopic structure quantitatively. Fiber tractography (FT) can visually display the direction and distribution of fiber bundles, providing more anatomical details non-invasively. Presently, the application of DTI in uterus has come to increasingly attention. DTI can well display fibrous structure of normal uterus and also be applied in uterine diseases, for instance, the differentiation of ordinary to degenerative uterine leiomyoma and postoperative efficacy evaluation after ultrasound ablation, the preoperative staging of endometrial and cervical cancer, determination of lymph node metastasis and prognosis evaluation, showing the microstructure of sacral nerve root to reflect the pathophysiological changes of endometriosis, providing more information for clinical diagnosis and contributes to the follow-up treatment options and prognosis evaluation.

Key words: Uterus, Uterine disease, Magnetic resonance imaging, Diffusion tensor imaging, Anisotropy

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