国际妇产科学杂志 ›› 2020, Vol. 47 ›› Issue (4): 417-421.

• 综述 • 上一篇    下一篇

阴道松弛症病因学研究进展

白军,郝玉婧,高艳萍△   

  1. 003700  山西省大同市,大同市第一人民医院/大同大学附属妇女儿童医院
  • 收稿日期:2020-03-26 修回日期:2020-04-14 出版日期:2020-08-15 发布日期:2020-08-15
  • 通讯作者: 高艳萍,E-mail:baijunjinanu@163.com E-mail:baijunjinanu@163.com

Research Progress of Vaginal Laxity Syndrome in Etiology

BAI Jun,HAO Yu-jing,GAO Yan-ping   

  1. The First People′s Hospital of Datong,Women′s and Children′s Hospital of Datong University,Datong 003700,Shanxi Province,China
  • Received:2020-03-26 Revised:2020-04-14 Published:2020-08-15 Online:2020-08-15
  • Contact: GAO Yan-ping,E-mail:baijunjinanu@163.com E-mail:baijunjinanu@163.com

摘要: 阴道松弛症(vaginal laxity syndrome,VLS)是妇科的常见病和多发病,可导致性生活满意度降低和(或)性功能障碍,常合并压力性尿失禁和女性生殖道炎症等疾病,严重影响女性身心健康,但其病因和发病机制尚未阐明。目前研究发现,妊娠、分娩、慢性阻塞性肺疾病、便秘、肥胖、长期负重、解剖学结构异常、生理性老化、医源性损伤、遗传和中医脏腑失调可引起阴道和维系阴道四维空间解剖结构的支持组织的损伤、血供障碍、神经支配异常及器官组织重塑,导致阴道紧缩、自净等生理功能下降,诱发VLS发生、发展。综述VLS的病因学进展,以更全面、更确切地揭示VLS发生、发展的机制及特点,更好地指导临床研究及治疗。

关键词: 阴道疾病;, 妊娠;, 分娩;, 骨盆底;, 阴道松弛症

Abstract: Vaginal laxity syndrome (VLS) is a common and frequently-occurring disease in gynecology, which can lead to decreased sexual satisfaction and/or sexual dysfunction and often combines with stress urinary incontinence and female genital tract inflammation and other diseases, severely affecting physical and mental health of women. However, its etiology and pathogenesis have not been disclosed. At present, studies found that factors like pregnancy, delivery, chronic obstructive pulmonary disease, constipation, obesity, long-term weight bearing, abnormal anatomical structure, physiological aging, iatrogenic injury, genetic and organ system dysfunction based on traditional Chinese medicine theories can cause the damage of vagina and its supporting tissues that sustain vagina′s four-dimensional anatomical structure. They can also cause blood supply disorders, abnormal innervation and organ tissue remodeling, resulting in a decline on physiological functions such as vaginal contraction, self-purification, inducing VLS development. This paper reviews the etiological progress of VLS, so as to reveal the mechanism and characteristics of VLS more comprehensively and accurately, and better guide the further clinical research and treatment.

Key words: Vaginal diseases;, Pregnancy;, Parturition;, Pelvic floor;, Vaginal laxity syndrome