Abstract: Objective：To explore the value of cadiovascular profile score （CVPS）to estimate fetal cadiac insufficiency. Methods：All pregnant women in ultrasound department，Tianjin Central Hospital of Gynecology Obstetrics proceeded routine examinations between Jan. 2013 and Jan. 2016. Fetal cardiac insufficiency (enlarged heart and myocardial contraction fatigue) were found out. CVPS were recorded. Meanwhile fetal cadiography were performed to define if congenital heart disease were accompanied. All cases divided in two groups based on the follow up results: live birth group and adverse pregnancy outcome group. Results：38 cases of fetal cardiac insufficiency were found out. 35 cases were singleton pregnancy. 3 cases were twins pregnancy. 12 cases were in live birth group (all of them were singleton pregnancy), 10 cases were healthy children, 2 cases were accompanied by congenital heart disease: 1 case was mild pulmonicstenosis, 1 case was tetralogy of Fallot. 21 cases were in adverse pregnancy outcome group. 18 cases were singleton pregnancies: 9 cases were intrauterine fetal demise, 2 cases were stillbirth, 7 cases were induced labour: 5 cases progressed to heart failure because of CVPS declined continuously and fetal cadiac insufficiency worsen, 2 cases were accompanied by fatal congenital heart disease. 2 cases of twins pregnancy were intrauterine fetal demise because of twin to twin transfusion syndrome (TTTS). 1 case of twins pregnancy was induced labour because of hydrocephaly and intracranial hemorrhage. 5 cases were loss to follow up. CVPS of live birth was 7.62 (7.00) and CVPS of adverse pregnancy outcomes was 5.67 (3.50). Statistics analysis: ROC curve analysis, area under ROC: 0.823, cut off value was 6.5, P=0.002, difference was statistically significant. The score of umbilical artery doppler spectrum, vein doppler spectrum and cardiac valve function in two groups were significant difference (P＜0.05). Conclusions：CVPS declined when fetal cardiac insufficiency worse, dangerous cut off value of CVPS was 6.5, CVPS is an effective index for continuous dynamic assessment of fetal cardiac insufficiency. The score of umbilical artery doppler spectrum, vein doppler spectrum and cardiac valve function were valuable to predict adverse pregnancy outcomes.

Key words: Ultrasonography，prenatal, Ultrasonography，Doppler，color, Fetal heart, Heart defects，congenital, Cadivascular profile score