Abstract: Cervical intraepithelial neoplasia （ＣＩＮ） is recognized as a kind of precursor lesion associated with cervical cancer. With the great progresses of cervical cancer biology research and screening techniques, early detection and treatment of high grade CIN has become the goal of prevention of cervical cancer. The major ethical and medical aim of all management options for CIN is the prevention of cervical cancer. To date, the "three-step" technique is still the primary way to detect and diagnose of CIN. For management of CIN, observational management was recommended for women with CINⅠ, whereas treatment of CINⅡ and CINⅢ should be excisional. Both loop electrosurgical excision procedure（LEEP） and laser conisation are accepted standard treatments for these patients. After treatment, cytology and human papillomavirus （ＨＰＶ） ｔesting are the best post-treatment monitoring for patients with low risk of tumor residue and recurrence, whereas colposcopy is recommended for patients with high risk of tumor residue and recurrence. The aim of this paper is to review the progresses of diagnosis, outcome, management and follow-up plan of CIN.