Abstract: The sentinel lymph node (SLN) is the first site of lymphatic metastasis of primary malignant tumors. It is possible to predict tumor metastasis in the entire lymphatic drainage area by detecting whether lymph node metastasis is in the SLN. At present, the research on SLN has been applied to the clinical diagnosis and treatment of malignant tumors such as breast cancer and melanoma. In gynecologic oncology, the researchers first carried out SLN research in vulvar cancer, and then carried out research on SLN detection and sentinel lymph node biopsy (SLNB) in cervical cancer and endometrial cancer, and have been applied in clinical practice. In this paper, the research status of SLN in endometrial cancer, cervical cancer, vulvar cancer and ovarian cancer at home and abroad and the problems that have yet to be solved are briefly summarized.

Key words: Sentinel lymph node biopsy, Endometrial neoplasms, Uterine cervical neoplasms, Vulvar neoplasms, Ovarian neoplasms