Abstract:

Ovarian cancer is a malignant tumor of the female reproductive system with the highest mortality rate. The early clinical symptoms of the disease are not obvious, and most of them are in the advanced stage at the time of consultation. In addition, due to recurrence and chemotherapy resistance, the prognosis is poor. It seriously threatens women′s life and health, which leads to arduous challenges in the clinical treatment of ovarian cancer. The traditional treatment of ovarian cancer is surgical treatment plus adjuvant chemotherapy. In recent years, with the improvement of surgical methods, the continuous improvement of chemotherapy regimens and the application of targeted drugs, the treatment of ovarian cancer has been continuously enriched. Although it has improved the prognosis of ovarian cancer to a certain extent, its overall survival rate is still poor. In addition, immunotherapy can take advantage of the autoimmune system. In recent years, it has received extensive attention in the treatment of ovarian cancer, but its clinical application still needs to be explored in depth. Therefore, further optimizing the treatment of ovarian cancer, increasing the survival rate of patients and improving their prognosis are the most difficult points in the treatment of ovarian cancer. The current status and latest progress of clinical treatment of ovarian cancer are reviewed, in order to provide new ideas for the treatment of ovarian cancer and further improve its prognosis.

Key words: Ovarian neoplasms, Gynecologic surgical procedures, Antineoplastic combined chemotherapy protocols, Molecular targeted therapy, Poly(ADP-ribose) polymerase inhibitors, Immunotherapy