Abstract:

Cervical adenoid basal cell carcinoma (ABC) is a rare malignancy that is frequently associated with high-risk human papillomavirus(HPV) infection and often coexists with high-grade squamous intraepithelial lesion(HSIL). Due to its nonspecific clinical manifestations, ABC is prone to misdiagnosis, and its pathogenesis remains unclear, posing diagnostic challenges. This report presents a postmenopausal patient with cervical ABC who was admitted to the First Affiliated Hospital of Guangzhou University of Chinese Medicine with the chief complaint of cervical lesion 3 days prior. Given the patient′s lack of fertility desire, a total hysterectomy with bilateral salpingo-oophorectomy was performed. No postoperative complications or recurrence has been observed during follow-up. By summarizing the etiology, clinical characteristics, and key diagnostic and therapeutic considerations of this disease, this case aims to enhance clinicians′ understanding of cervical ABC and improve diagnostic accuracy and management strategies.

Key words: Uterine cervical neoplasms, Carcinoma, basal cell, Squamous intraepithelial lesions, Human papillomavirus 18, Diagnosis, Therapy