浅表宫颈阴道肌纤维母细胞瘤切除术后复发一例并文献复习

doi:10.12280/gjfckx.20211188

国际妇产科学杂志 ›› 2022, Vol. 49 ›› Issue (3): 317-320.doi: 10.12280/gjfckx.20211188

• 妇科肿瘤研究:病例报告 • 上一篇下一篇

浅表宫颈阴道肌纤维母细胞瘤切除术后复发一例并文献复习

安静, 毕学汉, 康鹤遥, 杨永秀()

730000 兰州大学第一临床医学院（安静,康鹤遥）;兰州大学第一医院妇产科（毕学汉,杨永秀）;甘肃省妇科肿瘤重点实验室（安静,毕学汉,康鹤遥,杨永秀

收稿日期:2021-12-29 出版日期:2022-06-15 发布日期:2022-06-23
通讯作者: 杨永秀 E-mail:yongxiuyang@163.com

Recurrence of Superficial Cervicovaginal Myofibroblastoma after Resection: A Case Report and Literature Review

AN Jing, BI Xue-han, KANG He-yao, YANG Yong-xiu()

The First Clinical Medical College of Lanzhou University, Lanzhou 730000, China (AN Jing, KANG He-yao);Department of Obstetrics and Gynecology, The First Hospital of Lanzhou University, Lanzhou 730000, China (BI Xue-han, YANG Yong-xiu);Key Laboratory of Gynecological Oncology of Gansu Province, Lanzhou 730000, China (AN Jing, BI Xue-han, KANG He-yao, YANG Yong-xiu

Received:2021-12-29 Published:2022-06-15 Online:2022-06-23
Contact: YANG Yong-xiu E-mail:yongxiuyang@163.com

摘要/Abstract

摘要：

浅表宫颈阴道肌纤维母细胞瘤（superficial cervicovaginal myofibroblastoma,SCVM）是一种新近发现的较为罕见的良性肿瘤,具有相对独立的临床及病理特征,多发于绝经后妇女,主要发生在阴道、外阴及宫颈等部位,临床上易误诊及漏诊,易与纤维上皮性息肉、血管肌纤维母细胞瘤、富于细胞性血管纤维瘤等混淆,明确诊断需依靠病理学形态、免疫组织化学检测及临床资料。部分病例有明确服用抗雌激素类药物史,具有复发或再发的可能。回顾性分析兰州大学第一医院收治的1例SCVM复发患者的临床资料并复习文献,讨论SCVM的鉴别诊断,以提高对该肿瘤的认识。

关键词: 肿瘤,肌组织, 浅表宫颈阴道肌纤维母细胞瘤, 阴道, 肿瘤复发,局部, 诊断, 诊断,鉴别, 病理学, 免疫组织化学

Abstract:

Superficial cervicovaginal myofibroblastoma (SCVM) is a newly recognized and relatively rare benign tumor with independent clinical and pathological features. It mostly occurs in postmenopausal women, mainly in the vagina, vulva and cervix. It is easy to be misdiagnosed and clinically. It can easily be confused with fibrous epithelial polyps, angiomyofibroblastoma and cellular angiofibroma. A clear diagnosis depends on pathological morphology, immunohistochemistry and clinical data. Some cases have a clear history of taking anti-estrogen drugs and may have relapse or recurrence. Now we retrospectively analyze the clinical data of a patient with SCVM recurrence in the First Hospital of Lanzhou University, and review the literature, discuss its differential diagnosis, in order to improve the understanding of the tumor.

Key words: Neoplasms,muscle tissue, Superficial cervicovaginal myofibroblastoma, Vagina, Neoplasm recurrence,local, Diagnosis, Diagnosis,differential, Pathology, Immunohistochemistry

安静, 毕学汉, 康鹤遥, 杨永秀. 浅表宫颈阴道肌纤维母细胞瘤切除术后复发一例并文献复习[J]. 国际妇产科学杂志, 2022, 49(3): 317-320.

AN Jing, BI Xue-han, KANG He-yao, YANG Yong-xiu. Recurrence of Superficial Cervicovaginal Myofibroblastoma after Resection: A Case Report and Literature Review[J]. Journal of International Obstetrics and Gynecology, 2022, 49(3): 317-320.

图/表 4

图1 盆腔MRI矢状位图注：箭头示阴道左侧壁肿物2.5 cm×2.2 cm。

图2 阴道壁肿物病理图（HE染色×40）注：肿瘤位于黏膜下,无包膜,边界清楚。

图3 阴道壁肿物病理图（HE染色×200）注：肿瘤细胞核呈卵圆形或波浪状,细胞间见丰富的胶原,见薄壁血管。

图4 阴道壁肿物免疫组织化学染色（EnVision×100）注：肿瘤细胞ER阳性。

参考文献 15

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浅表宫颈阴道肌纤维母细胞瘤切除术后复发一例并文献复习

Recurrence of Superficial Cervicovaginal Myofibroblastoma after Resection: A Case Report and Literature Review

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