国际妇产科学杂志

国际妇产科学杂志 ›› 2010, Vol. 37 ›› Issue (1): 19-22.

• 综述 • 上一篇    下一篇

血清标志物早期诊断异位妊娠研究进展

王岚兰;郝 敏   

  1. 030001 太原，山西医科大学第二医院妇产科
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2010-02-15 发布日期:2010-02-15

Research Progress of Serum Markers for the Early Diagnosis of Ectoic Pregnancy

WANG Lan-lan;HAO Min   

  1. The Second Hospital of Shanxi Medical University， Taiyuan 030001， China
  • Received:1900-01-01 Revised:1900-01-01 Published:2010-02-15 Online:2010-02-15

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摘要： 异位妊娠是妇产科常见的急腹症，近二十年发病率呈上升趋势，提高诊断技术可减少异位妊娠误诊率及漏诊率，为保守治疗及保留输卵管的再生育功能创造有利条件。目前异位妊娠早期诊断主要依靠超声和血清人绒毛膜促性腺激素β亚单位（β-hCG）化验检查，但在妊娠4～5周时，尚不能完全确定妊娠部位。近年用于诊断异位妊娠的血清标志物的研究有一定进展，就有关异位妊娠早期诊断的血清标志物——血清hCG、孕激素、血管内皮生长因子、妊娠相关血浆蛋白、激活素-抑制素的研究进展做文献综述

关键词: 异位妊娠, 早期诊断, 血清标志物, 激活素-抑制素

Abstract: Ectopic pregnancy（EP） is a frequent surgical abdomen of obstetrics and gynecology，the incidence of which is rising in the recent twenty years. The developing of diagnostic techniques can reduce the rate of misdiagnosis and missed diagnosis， in order to create favorable conditions for better reserve fertility and conservative treatment of EP. The most common methods of early diagnosis of ectopic pregnancy are using ultrasound with serial measurements of human chorionic gonadotropin（β-HCG）. However， these cannot find the embryo as early as gestational 4-5weeks，not only for EP， but also for intrauterine pregnnacy. In recent years， research of diagnostic of serum markers for ectopic pregnancy have great progression， and this review will give a summarize， including human chorionic gonadotropin， progesterone， vascular endothelial grow factor，PAPP-A and activin-inhibin.

Key words: Ectopic pregnancy, Early diagnosis, Serum markers, Activin-inhibin