国际妇产科学杂志

国际妇产科学杂志 ›› 2011, Vol. 38 ›› Issue (6): 483-486.

• 综述 • 上一篇    下一篇

病原微生物对女性生殖健康的影响及其机制

张 丹 ,李静怡,黄荷凤   

  1. 310006 杭州袁浙江大学医学院附属妇产科医院
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2011-12-15 发布日期:2011-12-15
  • 通讯作者: 黄荷凤

Potential Effects and Mechanism of Pathogenic Microorganism on Female Reproductive Health

ZHANG Dan，LI Jing-yi，HUANG He-feng   

  1. Women's Hospital，School of Medicine，Zhejiang University，Hangzhou 310006，China
  • Received:1900-01-01 Revised:1900-01-01 Published:2011-12-15 Online:2011-12-15
  • Contact: HUANF He-feng

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摘要： 人类生育为病原微生物感染提供了良好的机会，妊娠妇女及其胎儿在受孕、妊娠、分娩到围生期的任何阶段都极易受到感染，病原微生物感染对生殖健康造成的影响主要视妊娠的不同阶段而定，而母体的免疫功能、营养状况以及并存的感染等也是影响因素。明确各种感染和生物因素对生殖功能的作用机制和阻断途径、对感染和生物因素的生殖毒作用进行早期预警和有效干预，是促进生殖健康、提高生殖质量的关键。就女性生育各阶段各种病原体感染与生殖相关疾病之间的关系及其作用机制综述。

关键词: 炎症, 早产, 不育, 女（雌）性, 生殖, 病原微生物, 感染

Abstract: Human reproduction provides favorable opportunities for the transmission of infectious agents. Furthermore，at either stage of reproduction，from conception to parturition and the neonatal period，mother and her offspring exhibit distinct susceptibilities to infection. The impact of pathogens on reproduction can be extenuated or exacerbated depending on stage of acquisition during pregnancy. Similarly，factors such as maternal immune response， nutritional status，or concurrent infection may modify the effect of a specific infectious agent. In this review，we discuss associations between infectious agents and reproductive problems at each stage of female reproduction and its potential mechanisms.

Key words: Inflammation, Premature birth, Infertility, female, Reproduction, Pathogenic microorganisms