国际妇产科学杂志

国际妇产科学杂志 ›› 2013, Vol. 40 ›› Issue (4): 339-342.

• 综述 • 上一篇    下一篇

子宫肌瘤药物治疗进展

张慧英,薛凤霞   

  1. 300052 天津医科大学总医院妇产科
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2013-08-15 发布日期:2013-08-15

Advances in the Medical Treatment of Uterine Leiomyomas Fibroids

ZHANG Hui-ying， XUE Feng-xia   

  1. Department of Obstetrics and Gynecology， Tianjin Medical University General Hospital, Tianjin 300052， China
  • Received:1900-01-01 Revised:1900-01-01 Published:2013-08-15 Online:2013-08-15

PDF (PC)

6642

被引次数

38

摘要： 子宫平滑肌瘤是女性生殖系统最常见的肿瘤，育龄妇女约20%患有子宫肌瘤。有些患者无症状，有些患者由于月经过多出现严重贫血。手术治疗是根治肌瘤的首选方案，但由于患者年龄及对生育的要求不同等原因，有些患者不愿手术，有些患者不宜手术，促性腺激素释放激素激动剂及米非司酮等药物可以通过降低体内雌激素水平抑制肌瘤的生长，并能使肌瘤缩小，改善肌瘤所致的临床症状，也是子宫肌瘤治疗的重要手段之一。

关键词: 子宫, 平滑肌瘤, 药物疗法, 促性腺素释放激素, 促性腺素释放激素激动剂, 选择性孕激素受体调节剂

Abstract: Uterine leiomyoma is the most common benign tumor of female reproductive system, which approximately 20% of women during reproductive years suffer from. Some patients are asymptomatic, while some suffer from severe anemia because of menorrhagia. As for treatment, surgery is the preferred solution for radical cure. However, due to the patients′ age and different fertility requirement, some patients do not want surgery, and some are not suitable for operation. Then gonadotropin-releasing hormone agonists and other drugs such as mifepristone can help reduce estrogen levels to inhibit the growth of myoma, and to make the myoma shrink, so as to improve clinical symptoms, which is one of another important treatments for uterine leiomyoma.

Key words: Uterus, Leiomyoma, Drug therapy, Gonadotropin-releasing hormone, Gonadotropin-releasing hormone agonists, Selective progesterone receptor modulators