Abstract: Liver transplantation is the final choice of the end-stage liver disease. Most of childbearing age women regain to normal life, hoping to bring up offspring. Although quite a few of these patients get conception and delivery without a hitch, still portion of them are infertile because of all kinds of reasons. Cases about infertile patients who had accepted assisted reproductive technology（ART） after organ transplantation are rare, since these not only refer to complicated ethical nature, but also require multi-disciplines collaboration. ART premises healthy pregnancy as well as minimizes maternal and fetal complications. This review introduced a case that a liver transplant patient who succeeded to be pregnant following intrauterine insemination and delivered at full-time, and also discusses the influences among graft, pregnancy and immunosuppressor.