国际妇产科学杂志

国际妇产科学杂志 ›› 2016, Vol. 43 ›› Issue (4): 420-423.

• 综述 • 上一篇    下一篇

卵巢透明细胞癌诊疗及预后

常敏会，史小荣   

  1. 030001 太原，山西医科大学第一医院妇科
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2016-08-15 发布日期:2016-08-15

Diagnosis，Treatment and Prognosis on Ovarian Clear Cell Carcinoma

CHANG Min-hui，SHI Xiao-rong   

  1. Department of Gynecology，First Hospital of Shanxi Medical University，Taiyuan 030001，China
  • Received:1900-01-01 Revised:1900-01-01 Published:2016-08-15 Online:2016-08-15

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摘要： 卵巢透明细胞癌（ovarian clear cell carcinoma，OCCC）是卵巢上皮细胞肿瘤中的一种特殊类型，发病率具有明显的地域差异，亚洲发病率居高。临床上以发病率较低、发现时国际妇产科联盟（FIGO）分期较早、治疗及时为其主要的特点。治疗严格按照FIGO分期进行分期手术，并在术后给予适当足疗程的化学治疗、放射治疗或其他治疗方案，但患者预后仍较差。化疗敏感性差是患者预后差的独立危险因素。OCCC患者的5年生存率与患者的肿瘤FIGO分期、术前CA125值是否高于150 U/mL、肿瘤细胞减灭程度、化疗方案的疗程是否足够有关。FIGO分期越早，术前CA125值≤150 U/mL、肿瘤切除干净、术后足疗程的化疗均可以提高患者的5年生存率。

Abstract: Ovarian clear cell carcinoma (OCCC) is a special type of ovarian epithelial tumors. Incidence has obvious regional differences, highly morbidity in Asia. Now OCCC has a low incidence in clinical, early onset for low FIGO staging, treatment in time for its main characteristics. Treatment in strict accordance with FIGO staging surgery, and give appropriately full course of chemotherapy, radiation therapy or other treatments after surgery. But patients′ prognosis is still poor. Patients with chemotherapy sensitivity as independent risk factors of prognosis. The 5-year survival rate of patients is associated with OCCC FIGO staging of tumor, preoperative CA125 values more than 150 U/mL or not, the radical remove degree of tumor cells, enough chemotherapy regimens of treatment. The earlier FIGO staging, preoperative CA125 values 150 U/mL or less, clean surgery of tumor resection and postoperative treatment of chemotherapy can improve the 5-year survival rate of patients.