国际妇产科学杂志

国际妇产科学杂志 ›› 2016, Vol. 43 ›› Issue (4): 467-470.

• 论著 • 上一篇    下一篇

中草药对子宫内膜异位症患者术后生存质量影响的Meta分析

肖超，赵静，覃正文   

  1. 643000 四川省自贡市妇幼保健院
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2016-08-15 发布日期:2016-08-15
  • 通讯作者: 覃正文

Effect of Chinese Herbal Medicine on Postoperative Quality of Life of Patients with Endometriosis：A Meta-Analysis

XIAO Chao，ZHAO Jing，QIN Zheng-wen   

  1. Zigong Maternal and Children Health Hospital，Zigong 643000，Sichuan Province，China
  • Received:1900-01-01 Revised:1900-01-01 Published:2016-08-15 Online:2016-08-15
  • Contact: QIN Zheng-wen

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摘要： 目的：系统评价中草药对子宫内膜异位症（EMs）患者术后生存质量的影响。方法：计算机检索Medline、EMBASE、The Cochrane Library、CNKI、中国生物医学文献数据库（CBM）、万方数据库。由2名研究者按照纳入与排除标准独立筛选文献、提取资料和评价文献质量后，采用RevMan 5.2软件进行Meta分析。结果：共纳入7篇文献，共计644例患者。Meta分析结果显示，依据世界卫生组织生存质量简化量表（WHOQOL-BREF）评分，中草药干预能够改善患者术后的总体生存质量[SMD=0.19，95%CI（0.11，0.28），P＜0.000 1]。此外，依据研究中的量表EHP-30/5评分，中草药可能提高了EMs患者术后生存质量。结论：研究结果显示中草药可改善EMs患者术后总体生存质量，然而研究中所用量表不是EMs的专用量表，且由于目前相关研究的质量和数量尚不足，还不能提供足够证据说明中草药的干预效果，尚需更高质量研究以增强论证强度。

Abstract: Objective: To systematic assess the effectiveness of Chinese herbal medicine on postoperative quality of life of patients with endometriosis. Methods: Such databases as Medline, EMbase, The Cochrane Library, CNKI, CBM, WanFang Database were electronically searched. According to the inclusion and exclusion criteria, literature was screened, data were extracted, and the methodological quality of included studies was also assessed by two researchers. Then, meta-analysis was performed using RevMan 5.2 software. Besides, based on EHP-30/5 scale scores, Chinese herbal medicines may improve the quality of life in patients with endometriosis after operation. Results: 7 studies with 644 participants were included. Evidence was found for significant effects on general quality of life [SMD=0.19, 95%CI （０．１１，０．２８）, P＜0.000 1], based on WHOQOL-BREF Scale. Conclusions: Because of the included study used different scales to assess quality of life, therefore, we can only research the final effect according to the different scale. This meta-analysis has found evidence for effects of Chinese herbal medicine on improving general quality of life for endometriosis patients after operation. However, the evidence is not strong enough because of low quality of the included studies. Therefore, more high quality researches are required.