国际妇产科学杂志 ›› 2018, Vol. 45 ›› Issue (5): 489-494.

• 综述 • 上一篇    下一篇

子宫浆液性癌的诊治进展

刘军秀,何勉,姚书忠,冯凤芝   

  1. 510080  广州,中山大学附属第一医院妇产科(刘军秀,何勉,姚书忠);中国医学科学院北京协和医学院北京协和医院妇产科(冯凤芝)
  • 收稿日期:2018-04-27 修回日期:2018-09-14 出版日期:2018-10-15 发布日期:2018-10-18
  • 通讯作者: 姚书忠,E-mail:yszlfy@163.com E-mail:yszlfy@163.com
  • 基金资助:
    国家自然科学基金(81502226,81672561)

Diagnosis and Treatment Advances in Uterine Serous Carcinoma

LIU Jun-xiu,HE Mian,YAO Shu-zhong,FENG Feng-zhi   

  1. Department of Obstetrics and Gynecology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China(LIU Jun-xiu,HE Mian,YAO Shu-zhong);Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medicine Sciences, Beijing 100730, China(FENG Feng-zhi)
  • Received:2018-04-27 Revised:2018-09-14 Published:2018-10-15 Online:2018-10-18
  • Contact: YAO Shu-zhong,E-mail:yszlfy@163.com E-mail:yszlfy@163.com

摘要: 子宫浆液性癌[USC,又称子宫乳头状浆液性癌(UPSC)],是非雌激素依赖性Ⅱ型子宫内膜癌的重要类型之一。其具有高度恶性的生物学特性:侵袭性强、术后复发率高,多灶性复发且病灶多位于盆腔以外的特点导致无法再用手术、放疗等方法进行挽救处理。因该病发病率不高,既往的小数据研究无法进行精细的分组统计,本文列举近年来多篇大数据回顾分析结果,并参照美国妇科肿瘤协会(SGO)与美国国立综合癌症网络(NCCN)对UPSC的治疗建议,介绍该病的临床特点,对不同FIGO分期的各种处理方式提供数据支持,旨在提高大家对该病的认识以掌握对该病的处理原则。

关键词: 子宫内膜肿瘤, 肿瘤, 囊性, 黏液性和浆液性, 诊断, 妇科外科手术, 抗肿瘤联合化疗方案, 放射疗法

Abstract: Uterine serous carcinoma(also known as Uterine papillary serous carcinoma ,UPSC ), is a main kind of estrogen-independent type Ⅱ uterine endometrial cancer. It is highly aggressive with high invasive ability, high recurrence rate after surgery. And the recurrent UPSC is often multifocal and the carcinoma is located outside the pelvic in most cases, leading to difficult situation which can′t be fixed with traditional treatment such as surgery or radiotherapy. Due to the low incidence rate of UPSC, previous study with limited cases can′t accomplish the classification and detailed statistical analysis. The present review lists recent articles with retrospective analysis of big data cases and introduces the clinical characteristics of UPSC with reference to treatment recommendation of the American Society of Gynecologic Oncology (SGO) and American National Comprehensive Cancer Network (NCCN), offering data support for various therapy choices for different FIGO stage patients. The present review also aims to improve the cognition of UPSC and help gynecologists to master the treatment principle of this disease.

Key words: Endometrial neoplasms, Neoplasms, cystic, mucinous, and serous, Diagnosis, Gynecologic surgical procedures, Antineoplastic combined chemotherapy protocols, Radiotherapy