国际妇产科学杂志 ›› 2018, Vol. 45 ›› Issue (1): 37-40.

• 论著 • 上一篇    下一篇

经皮神经电刺激用于分娩镇痛的临床研究

李莉,吕艳,翟翔隽,王冰,崔洪艳   

  1. 300100  天津市中心妇产科医院
  • 收稿日期:2017-11-24 修回日期:2018-01-15 出版日期:2018-02-15 发布日期:2018-02-15
  • 通讯作者: 崔洪艳,E-mail:cuihy9828@163.com E-mail:zxfclili@sina.com
  • 基金资助:
    天津市卫计委攻关基金项目(16KG112)

Clinical Study on Transcutaneous Electrical Nerve Stimulation in Labor Analgesia

 LI Li, LYU Yan, ZHAI Xiang-jun, WANG Bing, CUI Hong-yan   

  1. Tianjin Central Hospital of Gynecology Obstetrics, Tianjin 300100, China
  • Received:2017-11-24 Revised:2018-01-15 Published:2018-02-15 Online:2018-02-15
  • Contact: CUI Hong-yan,E-mail:cuihy9828@163.com E-mail:zxfclili@sina.com

摘要: 目的:观察经皮神经电刺激(TENS)合谷、三阴交、足三里穴用于分娩镇痛的临床效果并探讨其作用机制。方法:80例产妇随机分为2组,A组为TENS穴位组(临产后即予以TENS合谷、三阴交、足三里穴直至胎儿娩出);B组为对照组(不实施分娩镇痛)。记录2组产妇不同时点视觉模拟疼痛评分(VAS)、分娩结局及围生儿结局;于临产后(T0)、宫口开全时(T1)抽取静脉血检测2组产妇外周血β-内啡肽(β-EP)、皮质醇(Cor)及促肾上腺皮质激素(ACTH)的浓度。结果:A组产妇在产程潜伏期各时点VAS评分均低于B组,差异有统计学意义(P<0.05),但进入产程活跃期2组产妇VAS 评分差异无统计学意义(P>0.05);A组产妇产程时间短于B组,差异有统计学意义(P<0.05);2组产妇产后出血量、新生儿Apgar评分差异无统计学意义(P>0.05)。与T0时比较,2组产妇T1时外周血β-EP、Cor及ACTH浓度均升高(P<0.05);A组产妇T1时β-EP浓度高于B组(P<0.05),Cor及ACTH浓度低于B组(P<0.05)。结论:TENS合谷、三阴交、足三里穴可以很好地缓解潜伏期产痛,缩短产程,增加母婴安全性,其镇痛效果与β-EP含量明显增加及有效减少了产妇的应激反应有关,但活跃期镇痛不足是临床有待解决之处。

关键词: 经皮神经电刺激, 分娩, 镇痛, 分娩过程, 穴, 合谷, 穴, 三阴交, 穴, 足三里

Abstract: Objective: To observe the effects of electroacupuncture at Hegu, Sanyinjiao and Zusanli points in labor analgesia and to investigate the analgesic mechanism. Methods: 80 cases maternal were randomly divided into two groups, Group A: transcutaneous electrical nerve stimulation (TENS) group (Use TENS to Hegu, Sanyinjiao, Zusanli point in labor until the fetus was delivered); Group B: control group. Record VAS at different times, delivery outcome and perinatal outcome. Collect venous blood in both groups at the time of postpartum (T0), uterus opens to the full extent (T1) to test the concentration of β-EP, Cor and ACTH. Results: The VAS scores of group A were significantly lower than those of group B at each time points in incubation period of labor (P<0.05), but there was no significant difference in both groups after active phase of labor (P>0.05). The stage of labor in group A was shorter than that in group B (P<0.05). There was no significant difference in postpartum hemorrhage and Apgar score between two groups (P>0.05). Compared with T0, the concentrations of β-EP, Cor and ACTH in peripheral blood of both groups were significantly increased at T1 (P<0.05). The concentration of β-EP at T1 was significantly higher in group A than that in group B (P<0.05). Cor and ACTH concentrations were lower than those in group B (P<0.05). Conclusions: Electroacupuncture at Hegu, Sanyinjiao, Zusanli points can effectively relieve the pain in incubation period of labor, shorten the stage of labor and increase the safety of maternal-neonatal. Its analgesic effect was associated with the increase of neurotransmitter β-EP content and the effective reduction of maternal stress response. Further researches should be aimed to improve the analgesia effect in the active phase of labor.

Key words: Transcutaneous electrical nerve stimulation, Parturition, Analgesia, Labor, obstetric, Point LI4 (hegu), Point SP6 (sanyinjiao), Point ST36 (zusanli)