国际妇产科学杂志 ›› 2018, Vol. 45 ›› Issue (1): 33-37.

• 综述 • 上一篇    下一篇

胎儿大脑中动脉血流在高危妊娠中应用价值的研究进展

郑路路,乔媚,张田田,辛虹   

  1. 050000  石家庄,河北医科大学第二医院产科
  • 收稿日期:2017-10-18 修回日期:2018-01-04 出版日期:2018-02-15 发布日期:2018-02-15
  • 通讯作者: 辛虹,E-mail:xh_hbyd@163.com E-mail:xh_hbyd@163.com

Research Progress of the Application Value of Fetal Middle Cerebral Artery Blood Flow in High-Risk Pregnancies

ZHENG Lu-lu,QIAO Mei,ZHANG Tian-tian,XIN Hong   

  1. Department of Obstetrics,The Second Hospital of Hebei Medical University,Shijiazhuang 050000,China
  • Received:2017-10-18 Revised:2018-01-04 Published:2018-02-15 Online:2018-02-15
  • Contact: XIN Hong,E-mail:xh_hbyd@163.com E-mail:xh_hbyd@163.com

摘要: 胎儿大脑中动脉(MCA)是胎儿大脑血流供应最丰富的血管,对反映胎儿脑部血液循环改变及血氧情况的变化有重要的临床应用价值。正常妊娠时,随着孕周增加,胎儿脑部发育逐渐完善,胎儿MCA彩色多普勒超声血流信号指标的变化呈抛物线模式。在高危妊娠中,胎盘功能不足、血管阻力增加与不良妊娠结局之间呈一定的相关性。MCA具有自身调节功能,当胎儿的内外环境出现变化时如缺氧等可导致MCA的血流动力学发生改变,而胎儿MCA彩色多普勒超声的各项血流信号指标也呈异常的变化趋势。彩色多普勒超声检查胎儿MCA血流动力学指标对母儿双方安全、无创、方便以及可重复性高,可用来反映胎儿的一系列病理生理改变,成为近年来临床评估胎儿生长发育和宫内安危状况的重要监测手段。。

关键词: 胎儿, 大脑中动脉, 超声检查, 产前, 超声检查, 多普勒, 彩色, 胎儿生长迟缓, 胎儿窘迫

Abstract: Fetal middle cerebral artery (MCA) blood supply to the brain hemisphere is the most abundant blood vessel, which has more important clinical value in reflecting the dynamic changes in fetal cerebral circulation and blood oxygen status. In normal pregnancy, fetal brain development gradually improved with the increase of the gestational age, and the reference curve of blood flow parameters is characterized by a typical parabolic pattern for the color Doppler ultrasonography of fetal MCA. There is a certain correlation in high-risk pregnancies between the perinatal adverse pregnancy outcomes and placental deficiency or vascular resistance increase. Fetal MCA hemodynamics will show an abnormal change when internal and external environment changes such as hypoxia. The various blood flow signal indicators of the color Doppler ultrasonography of fetal MAC also will show an abnormal trend. Color Doppler ultrasound used to detect fetal MCA blood flow index is safe, non-invasive, convenient and reproducible to mother and fetal, can be used to reflect a series of pathophysiological changes in the fetal, and become a significant clinical tool in the evaluation of fetal growth status and intrauterine safety in recent years.

Key words: Fetus, Middle cerebral artery, Ultrasonography, prenatal, Ultrasonography, Doppler, color, Fetal growth retardation, Fetal distress