国际妇产科学杂志 ›› 2016, Vol. 43 ›› Issue (1): 75-79.

• 综述 • 上一篇    下一篇

预防性输卵管切除的应用价值与潜在风险

郑婷婷,李爱军,白晶   

  1. 450000 郑州大学第一附属医院妇科
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2016-02-15 发布日期:2016-02-15
  • 通讯作者: 李爱军

The Possible Advantages and Disadvantages of Prophylactic Bilateral Salpingectomy

ZHENG Ting-ting,LI Ai-jun,BAI Jing   

  1. Department of Gynecology,The First Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,China
  • Received:1900-01-01 Revised:1900-01-01 Published:2016-02-15 Online:2016-02-15
  • Contact: LI Ai-jun

摘要: 卵巢浆液性癌发病率呈逐年上升趋势,被视为发展最为迅猛的恶性肿瘤,临床发现时多为晚期。近年研究发现,输卵管伞端可能是女性盆腔浆液性癌前病变或癌的来源,输卵管腹膜接合部位(the fallopian tube-peritoneal junction,TPJ)可能与卵巢表面肿瘤有关。因子宫良性病变需切除子宫的绝经前女性,同时接受预防性双侧输卵管切除可能降低其患盆腔浆液性癌和卵巢表面肿瘤的风险。另外,有研究在输卵管组织发现间充质干细胞,其可作为多能干细胞新来源,并在修复生殖系统损伤中存在优势。综述盆腔肿瘤输卵管起源学说,预防性输卵管切除对盆腔良恶性病变的预防作用、术中及术后并发症,预防性输卵管切除在其他领域的应用价值,切除输卵管对卵巢功能的影响,探讨预防性输卵管切除的安全性及可行性。

关键词: 输卵管, 盆腔肿瘤, 间充质干细胞, 预防性输卵管切除

Abstract: The morbidity of ovarian serous cancer has been risen up in recent years. It develops rapidly to the terminal stages. Recent studies reveal that pelvic serous carcinoma or precancerosis may come from the fallopian tubal fimbria and the fallopian tube-peritoneal junction(TPJ) is possible related to the ovarian surface carcinoma. Prophylactic bilateral salpingectomy(PBS) in standard hysterectomy in premenopausal women with benign condition may be a strategy for preventing pelvic serous cancer and ovarian surface carcinoma. Besides,fallopian tube mesenchymal stem cells(FTMSC) have been found in fallopian tube,which can be a new source of multipotential stem cell.It is superior to other tissues in the reconstruction of genital system. To evaluate this procedure,we reviewed the theory of pelvic serous carcinoma associated with the fallopian tube, the effectiveness of PBS in reducing the risk of malignant or benign pelvic lesions, surgical or perioperative complications, the application of PBS in other fields as well as the effects of PBS on ovarian function.

Key words: Fallopian tubes, Pelvic neoplasms, Mesenchymal stem cells, Prophylactic bilateral salpingectomy