国际妇产科学杂志

国际妇产科学杂志 ›› 2011, Vol. 38 ›› Issue (2): 101-104.

• 综述 • 上一篇    下一篇

外阴阴道假丝酵母菌病治疗的研究进展

夏 艳 金志军   

  1. 200003 上海, 第二军医大学附属长征医院妇产科 夏艳(现就职于上海市长宁区中心医院),金志军
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2011-04-15 发布日期:2011-04-15

Progress on the Treatment of Vulvovaginal Candidiasis

XIA Yan, JIN Zhi-jun   

  1. Department of Gynecology and Obstetrics, Changzheng Hospital Affiliated to Second Military Medical University, Shanghai 200003, China
  • Received:1900-01-01 Revised:1900-01-01 Published:2011-04-15 Online:2011-04-15

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摘要： 外阴阴道假丝酵母菌病（VVC）是育龄期妇女的常见病。针对VVC的治疗方法主要有局部用药和口服用药，两种方法均有效。大量抗真菌药物的出现使选择用药出现争论。一般认为，唑类是首选用药，制霉菌素、两性霉素B和硼酸是二线用药，乳酸杆菌活菌制剂、精油疗法、抗过敏药为辅助用药。非传统疗法可治疗较顽固的病例。治疗中也需要考虑其他一些重要因素，包括妊娠、月经、药物敏感性、个人喜好等。

关键词: 念珠菌病, 外阴阴道, 念珠菌, 白色, 念珠菌, 光滑, 药物疗法

Abstract: Vulvovaginal candidiasis（VVC）is a common disease, occurring mostly in women of childbearing age. Currently available options for the treatment of VVC include local and oral therapy. Both alternatives are effective. The availability of numerous antifungal drugs for topical administration makes the selection quite challenging. Now it is generally considered that azoles is the preference, with nystatin, amphotericin B and boric acid considered as second-line alternatives, with lactobacillus, oils and antihistamine as adjuvant alternatives. Unconventional approaches may also be regarded as suitable in patients refractory to usual treatments. When treatment of VVC, some other important issues should be taken into consideration, such as pregnancy, menopause, drug hypersensitivity, women’s preference and so on.

Key words: Candidiasis, vulvovaginal, Candida albicans, Candida glabrata, Drug therapy