新型冠状病毒肺炎与妊娠

doi:10.12280/gjfckx.20201020

摘要/Abstract

摘要：

新型冠状病毒肺炎（COVID-19）于2019年12月在中国湖北武汉流行,2020年3月11日世界卫生组织（WHO）宣布疫情全球大流行。COVID-19是由新型冠状病毒（SARS-CoV-2）引起的,SARS-CoV-2在基因上与SARS病毒（SARS-CoV）相似,但不同于SARS-CoV。人类感染SARS-CoV-2后早期症状通常表现为发热和咳嗽。各个年龄段的人都可能被感染,其中新生儿、孕妇和老年人属于易感人群。在患有COVID-19的孕妇中,没有证据表明病毒会垂直传播,但早产率增加。COVID-19可能会改变母胎界面的免疫反应,影响母婴的健康。从免疫学的角度对孕妇患COVID-19的原因及其潜在的母婴并发症进行综述。

关键词: SARS病毒, 肺炎, 胎盘, 免疫, 妊娠结局, 治疗结果, 新型冠状病毒肺炎, 新型冠状病毒

Abstract:

COVID-19 was detected in December 2019 and became epidemic in Wuhan, Hubei Province, China. It was defined as a global pandemic by the World Health Organization (WHO) on March 11, 2020. COVID-19 is caused by the new virus labeled SARS-CoV-2. SARS-CoV-2 has been known to be genetically similar to SARS virus (SARS-CoV) but distinct from it. The infection typically presents as a fever and cough. It affects all age groups, including newborns, pregnant women to the elders. In pregnant women with COVID-19, there is no evidence for vertical transmission of the virus, but an increased prevalence of preterm deliveries. The COVID-19 may alter immune responses at the maternal-fetal interface and affect the well-being of mothers and infants. In this review, we focused on the reason why pregnant women are more susceptible to COVID-19 and the potential maternal and fetal complications from an immunological viewpoint.

Key words: SARS virus, Pneumonia, Placenta, Immunity, Pregnancy outcome, Treatment outcome, Novel coronavirus pneumonia, SARS-CoV-2

朱冉冉, 艾丽敏, 张丽颖. 新型冠状病毒肺炎与妊娠[J]. 国际妇产科学杂志, 2021, 48(4): 380-384.

ZHU Ran-ran, AI Li-min, ZHANG Li-ying. COVID-19 and Pregnancy[J]. Journal of International Obstetrics and Gynecology, 2021, 48(4): 380-384.

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