国际妇产科学杂志

国际妇产科学杂志 ›› 2009, Vol. 36 ›› Issue (6): 472-475.

• 综述 • 上一篇    下一篇

子宫内膜异位症动物模型活体无创观察研究

刘斌;王宁宁   

  1. 510080 广州，中山大学附属第一医院妇产科
  • 收稿日期:2008-11-28 修回日期:1900-01-01 出版日期:2009-12-15 发布日期:2009-12-15
  • 通讯作者: 王宁宁

Noninvasive Animal Models in Endometriosis Research

LIU Bin;WANG Ning-ning   

  1. Department of Obstetrics and Gynecology, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China
  • Received:2008-11-28 Revised:1900-01-01 Published:2009-12-15 Online:2009-12-15
  • Contact: WANG Ning-ning

PDF (PC)

4746

被引次数

7

摘要： 子宫内膜异位症（EMs）病因学和治疗学研究需要建立合适的疾病模型，既往对其研究的动物模型通常采用有创观察与病理相结合的研究方法，存在一定缺点。通过总结近5年开展的EMs动物模型活体无创观察方法的研究进展，分析每种方法的原理、方法和应用及相应的优缺点，探讨其改进方向，为EMs的基础研究和临床诊治提供重要观测依据。

关键词: 子宫内膜异位症, 体外, 无创, 动物模型, 荧光标记

Abstract: The animal model used for studying the etiological and therapeutic aspects of endometriosis needs improvement. Previous studies using invasive observation and pathological anatomy showed many disadvantages. In the article, we reviewed literature over the past five years where non-invasive endometriosis animal models were used. The principle, method and the application of each approach is analyzed. The pros and cons of the various kinds of models are listed, with the addition of suggested improvements of methods. This essential information will benefit basic research and the clinical management of endometriosis.

Key words: Endometriosis, In vivo, Noninvasive, Animal model, Fluorescent label