国际妇产科学杂志

国际妇产科学杂志 ›› 2010, Vol. 37 ›› Issue (2): 112-114.

• 综述 • 上一篇    下一篇

肿瘤干细胞在妇科肿瘤中的研究进展

姚婷婷,林仲秋   

  1. 510120 广州，中山大学附属第二医院妇产科
  • 收稿日期:2009-07-31 修回日期:1900-01-01 出版日期:2010-04-15 发布日期:2010-04-15
  • 通讯作者: 林仲秋

The Progress of Cancer Stem Cells in Gynecology Oncology

YAO Ting-ting, LIN Zhong-qiu   

  1. Department of Obstetrics and Gynecology, the Second Affiliated Hospital of Zhongshan University, Guangzhou 510120, China
  • Received:2009-07-31 Revised:1900-01-01 Published:2010-04-15 Online:2010-04-15
  • Contact: LIN Zhong-qiu

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摘要： 恶性肿瘤是严重威胁女性健康的疾病。转移与复发是妇科肿瘤治疗面临的两大难题。肿瘤干细胞学说认为，肿瘤组织中也存在少量具有干细胞性质的肿瘤干细胞，肿瘤干细胞是肿瘤发生、转移和复发的关键。肿瘤干细胞学说的提出，使通过靶向性杀伤肿瘤干细胞从而根治肿瘤成为可能。肿瘤干细胞和妇科肿瘤的相关研究进展综述。

关键词: 宫颈癌, 子宫内膜癌, 卵巢癌, 肿瘤干细胞

Abstract: Malignant tumors threaten women’s health. Metastasis and recurrence are the difficulties for cancer treatment. The theory of cancer stem cell proposes that the tumor tissue has its own cancer stem cells in it and regards cancer stem cell as the key to regeneration, metastasis and recurrence. The proposal of cancer stem cell concept provides the probability of radical curing cancers through the targeted killing of cancer stem cells. This article reviewed the progress of cancer stem cells in gynecology oncology.

Key words: Uterine cervical cancer, Endometrial cancer, Ovarian cancer, Cancer stem cells