国际妇产科学杂志

国际妇产科学杂志 ›› 2013, Vol. 40 ›› Issue (1): 81-83.

• 论著 • 上一篇    下一篇

南宁市妇女人乳头瘤病毒感染的流行病学调查

白 华, 黄 宁, 刘继秀   

  1. 530003 南宁,广西壮族自治区妇幼保健院妇科
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2013-02-15 发布日期:2013-02-15

Study on Human Papillomavirus Infection Among Women in Nanning

BAI Hua，HUANG Ning，LIU Ji-xiu   

  1. Department of Gynecology，the Maternal and Children′s Health Care Hospital of Guangxi Zhuang Autonomous Region，Nanning 530003，China
  • Received:1900-01-01 Revised:1900-01-01 Published:2013-02-15 Online:2013-02-15

PDF (PC)

5364

被引次数

28

摘要： 目的：了解南宁市妇女高危型人乳头瘤病毒（HR-HPV）的感染情况及其分布特点，初步探讨HR-HPV感染的相关因素。方法：2009年1月—2011年12月，采用整群抽样的方法，在南宁市抽取3 902例有性生活史的妇女进行妇科检查、宫颈HR-HPV检测，并进行问卷调查。应用SPSS13．0统计软件进行相关统计分析。结果：①南宁市18～73岁妇女HPV感染率为23.9％。②HPV感染的年龄分布特点：＜20岁年龄段感染率最高，为91.3%，25～49岁年龄段的感染率约为20％，处于较稳定的水平，不同年龄组HPV感染率差异有统计学意义（χ2=170.404 3，P =0.000）。不同职业及不同民族妇女HPV感染率差异无统计学意义（均P＞0.05）。③南宁市妇女的HPV感染以52， 16，58和18型为主，而多重感染百分率为36.3%，均为高危型多重感染或高危型合并低危型多重感染。结论：南宁市不同年龄妇女的HPV感染率存在差异，其感染的危险因素为多个性伴者、妊娠分娩数＞1，对HPV持续阳性的妇女应加强监测，以早期发现宫颈病变及宫颈癌。

关键词: 南宁地区, 乳头状瘤病毒科, 流行病学, Logistic模型

Abstract: Objective：To investigate high risk human papillomavirus（HR-HPV） prevalence among women in Nanning
and to study the high risk factors． Methods：During January 2009 to December 2011，a total of 3 902 women sampled in Nanning by HR-HPV DNA test and cytological tesk.The interview was carried out with unified questionnaires．The data were analyzed in SPSS 13.0． Results：①The HPV infection rate was 23．9％． ②The age distribution of HPV infection was the highest（91.3％） in＜20 age group；then the rate was descended as the age raising，the rate of 25 to 49 age group was stable at 20％，HPV infection rate of different age groups was highly statistically significant（χ2 = 170.404 3； P= 0.000）. In different occupations and different ethnic women HPV infection rate was not statistically significant. ③The positive rate of HPV detection in genotyping assay group was HPV-52，16，58，18，respectively. The percentage of multiple infections was 36.3%，both are high risk of multiple infections or high-risk with low-risk type of multiple infections. Conclusions：The HPV infection rate among different aged women was significant difference,the high risk population which should strengthen screening was the women with more than one sexual partner or more than one pregnancy,the sustained infection women should be checked regularly intend to early detection of cervical lesions and cervical cancer.

Key words: Nanning, Papillomaviridae, Epidemiology, Logistic models