外阴鳞状细胞癌的诊治进展

doi:10.12280/gjfckx.20210298

摘要/Abstract

摘要：

外阴鳞状细胞癌（vulval squamous cell carcinoma,VSCC）的发病率逐年增加,虽然肿瘤的诊治水平不断进步,但晚期VSCC的复发率和死亡率没有明显降低。由于VSCC罕见,目前尚无随机临床试验比较不同治疗方式的优劣。传统的治疗方案以手术和放疗为主,手术方式的变化趋势倾向于更为保守的手术范围获得更大的疾病治疗的效果,腹腔镜下腹股沟淋巴结清扫和前哨淋巴结活检的应用也逐渐广泛,目前免疫治疗也正在兴起。综述目前VSCC在诊断、手术治疗和放化疗相关方面的最新研究进展,以期为后续的临床诊治提供参考。

关键词: 外阴肿瘤, 癌,鳞状细胞, 乳头状瘤病毒科, 妇科外科手术, 放化疗,辅助, 前哨淋巴结, 前哨淋巴结活组织检查, 预后

Abstract:

The incidence of vulvar squamous cell carcinoma (VSCC) increases every year. Although the diagnosis and treatment of tumors are improving, the recurrence rate and death rate of late VSCC have not decreased obviously. Due to the rarity of VSCC, there are no randomized clinical trials to compare the advantages and disadvantages of different treatments. Traditional treatments mainly include surgery and radiotherapy, and the changing trend of the surgical methods tends to be more conservative surgical scope to achieve greater therapeutic effect for diseases. The application of laparoscopic inguinal lymph node dissection and sentinel lymph node biopsy is also gradually widespread, and immunotherapy is also on the rise. The purpose of this paper is to review the latest research progress in the diagnosis, surgical treatment, radiotherapy and chemotherapy of VSCC, to provide reference for follow-up clinical diagnosis and treatment.

Key words: Vulvar neoplasms, Carcinoma,squamous cell, Papillomaviridae, Gynecologic surgical procedures, Chemoradiotherapy,adjuvant, Sentinel lymph node, Sentinel lymph node biopsy, Prognosis

秦昭娟, 郑艾. 外阴鳞状细胞癌的诊治进展[J]. 国际妇产科学杂志, 2022, 49(1): 34-38.

QIN Zhao-juan, ZHENG Ai. Progress in Diagnosis and Treatment of Vulvar Squamous Cell Carcinoma[J]. Journal of International Obstetrics and Gynecology, 2022, 49(1): 34-38.

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