Abstract:

Epithelioid trophoblastic tumor (ETT) is a malignant tumor derived from chorioamniotic intermediate trophoblast. ETT is often related to the previous pregnancy history, most of which are secondary to the previous normal pregnancy, while ETT patients who are secondary to gestational trophoblastic neoplasia (GTN) are very rare. A patient with ETT secondary to the previous hydatidiform mole underwent uterine curettage because of hydatidiform mole, and hysteroscopic surgery was performed 2 years later because of abnormal uterine bleeding. The disease was found and was considered as ETT with suspected lung metastasis. The prognosis of the patients was good after hysterectomy and adjuvant chemotherapy. Combined with related case reports, the clinical features, such as onset time, location, ultrasound, pathology and immunohistochemistry, treatment and prognosis of this kind of ETT were summarized in order to improve clinicians′ understanding of the disease and make efforts to improve the treatment and prognosis of the disease.

Key words: Uterine neoplasms, Trophoblastic neoplasms, Diagnosis, Therapy, Prognosis, Case reports, Epithelioid trophoblastic tumor