Journal of International Obstetrics and Gynecology ›› 2023, Vol. 50 ›› Issue (2): 228-233.doi: 10.12280/gjfckx.20220423

• Research on Gynecological Malignancies: Case Report • Previous Articles     Next Articles

Glassy Cell Cervical Carcinoma:A Case Report and Literature Review

WANG Yao, YANG Jia-xin()   

  1. Department of Obstetrics and Gynecology, China-Japan Friendship Hospital, Beijing 100029, China (WANG Yao); Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100730, China (YANG Jia-xin)
  • Received:2022-05-30 Published:2023-04-15 Online:2023-04-24
  • Contact: YANG Jia-xin, E-mail: yangjiaxin_2017@163.com

Abstract:

Glassy cell cervical carcinoma (GCCC) is a very rare form of cervical carcinoma, which belongs to the low-differentiated subtype of adenosquamous carcinoma, and the related reports at home and abroad are few. Due to its rarity and particularity, there are currently no relevant guidelines for diagnosis and treatment of this disease. This article reports the diagnosis and treatment process of a 43-year-old patient with stage ⅡB GCCC who underwent laparoscopic total hysterectomy combined with bilateral adnexectomy after concurrent chemoradiotherapy, and was also given 3 courses of adjuvant chemotherapy with paclitaxel and cisplatin. However, in a short period of time, there have been multiple metastases throughout the body. The patient responded poorly to multiple chemotherapy regimens and was eventually lost. This article reviews the relevant literature both domestic and abroad, aiming to improve the understanding, diagnosis and treatment of the disease, and provide more reference for diagnosis and treatment for follow-up study of this disease.

Key words: Uterine cervical neoplasms, Diagnosis, Therapy, Prognosis, Case reports