Journal of International Obstetrics and Gynecology ›› 2023, Vol. 50 ›› Issue (4): 366-371.doi: 10.12280/gjfckx.20230139

• Research on Gynecological Malignancies: Review • Previous Articles     Next Articles

Advances in Diagnosis and Treatment of Cervical Mucinous Adenocarcinoma

SONG Xiao-xing, TIAN Ting-ting, SHI Hui-rong, JIA Yan-yan()   

  1. The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China(SONG Xiao-xing, TIAN Ting-ting);Department of Gynecology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China (SHI Hui-rong, JIA Yan-yan)
  • Received:2023-02-27 Published:2023-08-15 Online:2023-08-15
  • Contact: JIA Yan-yan, E-mail: fccjiayy@zzu.edu.cn

Abstract:

Cervical mucinous adenocarcinoma is a rare and special histological type of cervical malignant tumor, which mainly includes adenocarcinoma of the cervix gastric type, adenocarcinoma of the cervix and intestines, and primary cervical signet-ring cell carcinoma. Due to the uncertainty between the pathogenesis of cervical mucinous adenocarcinoma and human papillomavirus (HPV) infection makes it difficult to be suggested by routine cervical cancer screening. Meanwhile, the etiology and pathogenesis of cervical mucinous adenocarcinoma are not clear, and there is a lack of typical clinical manifestations and early diagnosis methods, and the clinicopathological features and treatment are different from those of cervical common adenocarcinoma, resulting in patients being prone to miss the best treatment time, so the prognosis of cervical mucinous adenocarcinoma is worse than that of cervical common adenocarcinoma. In recent years, due to the popularization of HPV vaccine, the relative incidence of cervical mucinous adenocarcinoma has slightly increased compared with before, and the research on cervical mucinous adenocarcinoma has received more and more attention. The relevant research on cervical mucinous adenocarcinoma at home and abroad is reviewed, and the relevant pathogenesis, clinical features and treatment of cervical mucinous adenocarcinoma are discussed, in order to provide a reference for the clinical diagnosis and treatment of cervical mucinous adenocarcinoma.

Key words: Uterine cervical neoplasms, Adenocarcinoma, mucinous, Adenocarcinoma of the cervix gastric type, Adenocarcinoma of the cervix and intestines, Primary cervical signet-ring cell carcinoma, Diagnosis, Therapy, Prognosis