Research Progress of Premenopausal Endometrial Polyps, Postmenopausal Endometrial Polyps and Tamoxifen-Associated Endometrial Polyps

doi:10.12280/gjfckx.20230805

Abstract

Abstract:

Endometrial polyp (EP) is a common lesion of the endometrium, which can be classified as premenopausal EP, postmenopausal EP, and Tamoxifen (TAM)-associated EP. Different types of EP have different clinical features and treatment. Ageing, menopause, and the use of TAM are high-risk factors for the development and malignancy of EP. The expression of steroid hormone receptors varies among the three types of EP due to the influence of different factors such as hormone levels in women. Premenopausal EP usually exhibits the classic pathological features of EP, postmenopausal EP has a richer mesenchymal stroma, and TAM-associated EP may be accompanied by atypical hyperplasia and carcinoma. Premenopausal EP is usually a homogeneous hypoechoic mass on ultrasound, while postmenopausal EP often shows multiple cystic foci of varying sizes, and TAM-associated EP often shows densely distributed honeycomb-like liquid dark areas. The treatment approaches for different types of EP are not entirely the same and should be personalized based on factors such as whether the patient is menopausal or not, with or without symptoms and fertility requirements, and risk of malignancy.

Key words: Endometrial polyp, Premenopause, Postmenopause, Tamoxifen, Ultrasonography, Therapy

WANG Qi-qin, WANG Xiang-lian, PAN Si-yi, WANG Xiu-li. Research Progress of Premenopausal Endometrial Polyps, Postmenopausal Endometrial Polyps and Tamoxifen-Associated Endometrial Polyps[J]. Journal of International Obstetrics and Gynecology, 2024, 51(2): 137-141.

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