Abstract:

Adenoid cystic carcinoma (ACC) is a rare malignant epithelial tumor originating from salivary gland tissue. The occurrence of ACC in the cervix is even rarer, representing for only 1% of all cervical adenocarcinomas. It is highly invasive, has a poor prognosis, and lacks a standard treatment plan. This article reports the diagnosis and treatment of a patient with cervical ACC combined with basal cell carcinoma and squamous cell carcinoma. The patient, an elderly woman, was admitted to the hospital for a newly discovered mass at the vaginal opening accompanied by intermittent vaginal bleeding. The pathological biopsy results of the vaginal mass showed malignant tumors, consistent with ACC; she underwent laparoscopic pelvic lymph node dissection + total hysterectomy + high ovarian arteriovenous ligation (bilateral) + bilateral ovarian and fallopian tube resection + intestinal adhesion lysis + mesenteric neoplasm resection. Postoperative pathology showed cervix mixed cancer composed of ACC, adenoid basal cell carcinoma and squamous cell carcinoma, along with local non-specific spindle cell sarcomatoid stroma. She received two cycles of chemotherapy and one session of radiotherapy postoperatively; the patient recovered well after surgery, and no metastasis or recurrence was found in regular follow-up examinations until January 22, 2024.

Key words: Uterine cervical neoplasms, Diagnosis, Therapy, Prognosis, Case reports