Journal of International Obstetrics and Gynecology ›› 2024, Vol. 51 ›› Issue (4): 384-387.doi: 10.12280/gjfckx.20240004

• Research on Gynecological Malignancies: Case Report • Previous Articles     Next Articles

Malignant Transformation of Mature Cystic Teratoma of Ovary: A Case Report

JI An-xuan, ZHAO Shu-hua()   

  1. Department of Obstetrics and Gynecology, The Second Hospital of Jilin University, Changchun 130000, China
  • Received:2024-01-03 Published:2024-08-15 Online:2024-07-25
  • Contact: ZHAO Shu-hua, E-mail: zhaoshuhua-1966@163.com

Abstract:

Mature cystic teratoma of ovary (MCTO) is the most common ovarian germ cell tumor, which is usually benign. However, in rare cases, it may undergo malignant transformation. Malignant transformation of MCTO (MT-MCTO) is common in postmenopausal women. Due to its rarity, there is still no standard diagnosis and therapeutic options. This paper reports the diagnosis and treatment of a 77-year-old patient with MT-MCTO to squamous cell carcinoma at stage ⅡB. After cytoreductive surgery, the patient received a course of chemotherapy with bleomycin+etoposide +cisplatin. However, because the patient's physical condition could not tolerate further treatment, the patient died after six months of postoperative follow-up.

Key words: Teratoma, Ovarian neoplasms, Carcinoma, squamous cell, Therapy, Prognosis