Abstract: Target therapy focus on the tumor's characteristics which are different from normal tissues. So as to gain higher therapeutic effect with lower adverse effect. At present，most of the research of target therapy is about anti-vascular therapy.Intense researches and development activities have resulted in a variety of investigational agents，a number of which are currently be used in clinical experiments. This paper reviewed the clinical trials of anti-vascular target therapy in ovarian cancer，in order to know about the current situation and the prospective research of the treatment in ovarian cancer.

Key words: Ovarian neoplasms, Vascular endothelial growth factors, Therapy, Clinical trial