Abstract: Objective：To explore the clinical features，diagnosis and treatment of mirror syndrome. Methods：The clinical data including clinical symptoms and physical signs，laboratory and ultrasound examination，gross and microscopic placental examination and outcomes of both mother and fetus in 6 cases with mirror syndrome at our hospital from 2009 to 2010 were analyzed retrospective，and relative literatures were reviewed. Results：6 cases with mirror syndrome was presented the triad of maternal edema，hydrops fetalis and hydropic placenta. 6 cases have several characteristics such as anemia and hemodilution［Hb（86.00±10.88） g/L和HCT 0.267 7±0.026 7］， hypopoteinemia［ALB（ 21.53 ± 3.12） g/L］， albuminuria and proteinuria，elevated uric acid ［UA（551.50±63.02） μmo/L］.In addition，elevated blood pressure was present in 4 cases. Conclusions：Mirror syndrome can be diagnosed as the development of maternal edema in association with hydrops fetalis or hydropic placenta. Some cases can present preeclampsia-like symptoms.An important characteristic of mirror syndrome that distinguishes it from preeclampsia is maternal hemodilution. Once mirror syndrome is diagnosed，the cause of hydrops should be corrected as soon as possibly. Diuretic and limitation of fluid input volume also should be considered.

Key words: Hydrops fetalis, Placenta, Pre-eclampsia, Diagnosis, Therapy, Case reports