Journal of International Obstetrics and Gynecology ›› 2014, Vol. 41 ›› Issue (3): 252-255.

• 综述 • Previous Articles     Next Articles

MicroRNA in Cervical Cancer

WANG Hong-hong,HAO Min,ZHAO Wei-hong   

  1. The Second Hospital of Shanxi Medical University,Taiyuan 030001,China
  • Received:1900-01-01 Revised:1900-01-01 Published:2014-06-15 Online:2014-06-15
  • Contact: HAO Min

Abstract: MicroRNA(miRNA) is a family of 18-25 nucleotide non-coding RNA. Accumulating evidence indicated that miRNA played an important role in regulating the cells,proliferation,apoptosis and tumorigenesis. miRNA may be closely associated with a variety of tumor occurrence,development,invasion and metastasis. Great concern has been raised regarding the correlation between cervical cancer and miRNA recently. The aberrant expressions of several miRNAs in cervical cancer were demonstrated to be involved in the occurrence and development of cervical cancer. However researches on the abnormal expression and regulation mechanism of the miRNA in cervical cancer were not much,still need further research. Here is to discuss the relationship between miRNA and cervical cancer and the possible regulation mechanism of the abnormal expression of miRNA.

Key words: MicroRNAs, Uterine cervical neoplasms, Papillomaviridae, Epigenesis, genetic