Journal of International Obstetrics and Gynecology ›› 2014, Vol. 41 ›› Issue (4): 401-404.

• 综述 • Previous Articles     Next Articles

Related Research of Endometrial Cancer and microRNA

LIU Qi-wei,YANG Min,TONG Xiao-wen,WANG Jian-jun   

  1. Medical College,Tongji University,Shanghai 200092,China(LIU Qi-wei,YANG Min);Department of Obstetrics and Gynecology,Tongji Hospital,Shanghai 200065,China(TONG Xiao-wen,WANG Jian-jun)
  • Received:1900-01-01 Revised:1900-01-01 Published:2014-08-15 Online:2014-08-15
  • Contact: WANG Jian-jun

Abstract: microRNAs(miRNAs) are non-coding RNAs that can regulate mRNA in the level of post-translational modification,transcription and post-transcription. And they are associated with growth,development and invading of tumors as oncogenic miRNAs and tumor suppressor miRNAs. Relationships of miRNAs with endometrial cancer(EC) have recently emerged. For instance,miRNA-200 family,miRNA-205,miR-129-2,miR-203,miR-302,miR-194,miR-30c,miR-204,miR-34,miR-125,miRNA-152,miRNA-503,etc. With the deeper research,miRNAs may be used in clinical applications as one of new targets. In this article,there is an overview about the recent research of miRNAs and EC.

Key words: Endometrial neoplasms, Carcinoma, MicroRNAs, Forecasting, Therapy