A Case Report on Treatment of Cervical Ectopic Pregnancy Using High Intensity Focused Ultrasound Combined with Curettage

doi:10.12280/gjfckx.20201175

Abstract

Abstract:

As one of ectopic pregnancies, cervical ectopic pregnancy, which is rare in clinic, may cause severe bleeding and other adverse outcomes because the embryo is implanted in the cervical mucosa. In some severe cases, hysterectomy is necessary and it would be even life-threatening while there is no specific method to treat the disease and individualized treatment is needed. At present, there are few reports on the treatment of cervical ectopic pregnancy by high intensity focused ultrasound. Now, a female diagnosed with cervical ectopic pregnancy who was hospitalized in the Department of Obstetrics and Gynecology, The Characteristic Medicine Center of The Chinese People′s Armed Police Forces in 2020 cured by high intensity focused ultrasound combined with curettage is reviewed. We hope to share the treatment experience in order to attract the attention of obstetricians and gynecologists, and strive for more effective, safer and more economic treatment for cervical ectopic pregnancy patients.

Key words: High-intensity focused ultrasound, Dilatation and curettage, Pregnancy,ectopic, Case reports, Cervical ectopic pregnancy

ZHANG Xiao-rong, MA Yan-wei, DONG Qu-long, HOU Hai-yan, YANG Zhen-hua. A Case Report on Treatment of Cervical Ectopic Pregnancy Using High Intensity Focused Ultrasound Combined with Curettage[J]. Journal of International Obstetrics and Gynecology, 2021, 48(5): 525-527.

Figures/Tables 2

References 14

[1]	Raba G, Baran P, Szczupak K. Combined treatment of cervical pregnancy with methotrexate and prostaglandins[J]. J Obstet Gynaecol India, 2015,65(2):122-124. doi: 10.1007/s13224-014-0555-y. doi: 10.1007/s13224-014-0555-y
[2]	Ozcivit IB, Cepni I, Hamzaoglu K, et al. Conservative management of 11 weeks old cervical ectopic pregnancy with transvaginal ultrasound-guided combined methotrexate injection: Case Report and Literature Review[J]. Int J Surg Case Rep, 2020,67:215-218. doi: 10.1016/j.ijscr.2020.01.020. doi: 10.1016/j.ijscr.2020.01.020
[3]	Ahmadi F, Irani S. Cervical Ectopic Pregnancy following Assisted Reproductive Technology: A Case Report[J]. Int J Fertil Steril, 2012,6(3):201-204.
[4]	Murji A, Garbedian K, Thomas J, et al. Conservative Management of Cervical Ectopic Pregnancy[J]. J Obstet Gynaecol Can, 2015,37(11):1016-1020. doi: 10.1016/s1701-2163(16)30051-2. doi: 10.1016/s1701-2163(16)30051-2 pmid: 26629722
[5]	Masselli G, Derme M, Piccioni MG, et al. To evaluate the feasibility of magnetic resonance imaging in predicting unusual site ectopic pregnancy: a retrospective cohort study[J]. Eur Radiol, 2018,28(6):2444-2454. doi: 10.1007/s00330-017-5237-6. doi: 10.1007/s00330-017-5237-6
[6]	Stabile G, Mangino FP, Romano F, et al. Ectopic Cervical Pregnancy: Treatment Route[J]. Medicina(Kaunas), 2020,56(6):293. doi: 10.3390/medicina56060293. doi: 10.3390/medicina56060293
[7]	连成瑛, 陈秀娟, 黄小琛, 等. 宫颈妊娠的诊断与治疗[J]. 中国妇幼保健, 2018,33(22):5070-5073. doi: 10.7620/zgfybj.j.issn.1001-4411.2018.22.08. doi: 10.7620/zgfybj.j.issn.1001-4411.2018.22.08
[8]	Elhelf I, Albahar H, Shah U, et al. High intensity focused ultrasound: The fundamentals, clinical applications and research trends[J]. Diagn Interv Imaging, 2018,99(6):349-359. doi: 10.1016/j.diii.2018.03.001. doi: 10.1016/j.diii.2018.03.001
[9]	Cheung V. High-intensity focused ultrasound therapy[J]. Best Pract Res Clin Obstet Gynaecol, 2018,46:74-83. doi: 10.1016/j.bpobgyn.2017.09.002. doi: 10.1016/j.bpobgyn.2017.09.002
[10]	Marques A, Andres MP, Kho RM, et al. Is High-intensity Focused Ultrasound Effective for the Treatment of Adenomyosis? A Systematic Review and Meta-analysis[J]. J Minim Invasive Gynecol, 2020,27(2):332-343. doi: 10.1016/j.jmig.2019.07.029. doi: 10.1016/j.jmig.2019.07.029
[11]	Lee JS, Hong GY, Park BJ, et al. High-intensity focused ultrasound combined with hysteroscopic resection to treat retained placenta accreta[J]. Obstet Gynecol Sci, 2016,59(5):421-425. doi: 10.5468/ogs.2016.59.5.421. doi: 10.5468/ogs.2016.59.5.421
[12]	王玉楣, 李双弟, 王蓓颖, 等. 高强度聚焦超声消融治疗子宫肌瘤时妊娠一例报告并文献复习[J]. 国际生殖健康/计划生育杂志, 2020,39(3):256-259. doi: 10.3969/j.issn.1674-1889.2020.03.019. doi: 10.3969/j.issn.1674-1889.2020.03.019
[13]	徐锋, 镡丽霞, 李盼, 等. 高强度聚焦超声消融联合GnRHa治疗子宫腺肌病的临床研究[J]. 国际妇产科学杂志, 2019,46(6):618-620,640. doi: 10.3969/j.issn.1674-1870.2019.06.004. doi: 10.3969/j.issn.1674-1870.2019.06.004
[14]	Jiang J, Xue M. The treatment of cervical pregnancy with high-intensity focused ultrasound followed by suction curettage: report of three cases[J]. Int J Hyperthermia, 2019,36(1):273-276. doi: 10.1080/02656736.2018.1563914. doi: 10.1080/02656736.2018.1563914

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