Correlation of Vaginal Microecology with HPV Positivity and Cervical Lesions

doi:10.12280/gjfckx.20230018

Abstract

Abstract:

Cervical cancer is one of the most common malignancies of the female reproductive tract worldwide, and its incidence has been increasing year by year in recent years. The etiology of cervical cancer is relatively clear, almost all cases of cervical cancer being associated with human papilloma virus (HPV) infection. In addition, poor lifestyle habits such as multiple sexual partners, young age at first sex and smoking are high risk factors for cervical lesions. In recent years, with the continuous research on vaginal microecology, researchers have discovered that vaginal microecology can regulate HPV infection and play a crucial role in the development of cervical precancerous lesions and invasive cervical cancer, which may serve as a potential biomarker for cervical cancer detection. In-depth study of the intrinsic link between vaginal microecology, cervical lesions and HPV infection is of great significance for the prevention and early treatment of cervical cancer.

Key words: Uterine cervical neoplasms, Cervical intraepithelial neoplasia, Lactobacillus, Papillomaviridae, Papillomavirus vaccines, Vaginal microecology

CONG Rong, ZHAI Qing-zhi. Correlation of Vaginal Microecology with HPV Positivity and Cervical Lesions[J]. Journal of International Obstetrics and Gynecology, 2023, 50(3): 286-289.

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