Abstract:

Ovarian immature teratoma is a common ovarian germ cell malignant tumor that occurs in adolescent females. Surgical resection is the main treatment, and postoperative adjuvant chemotherapy is required if necessary. This case is an immature differentiated teratoma in the left ovary found during cesarean section. After 3 courses of chemotherapy with BEP regimen, the liver teratoma metastasis occurred. The pathological results after the second tumor resection suggest that mature teratoma is considered as growing teratoma syndrome (GTS). During the course of follow-up, the liver lesions were suspicious and reappeared, but gradually disappeared. Follow-up for 1 year showed no recurrence. During the treatment of ovarian immature teratoma, GTS is rare, has a special pathogenesis, and is easily misdiagnosed as recurrence or progression of ovarian immature teratoma. Therefore, it is necessary to understand GTS and pay attention to it in clinical practice.

Key words: Ovarian immature teratoma, Teratoma, Ovarian neoplasms, Liver metastasis, Neoplasm metastasis, Liver neoplasms, Growing teratoma syndrome, Therapy, Case reports