Journal of International Obstetrics and Gynecology ›› 2024, Vol. 51 ›› Issue (5): 597-600.doi: 10.12280/gjfckx.20240193

• Research on Gynecological Malignancies: Case Report • Previous Articles    

Cervical Carcinosarcoma:A Case Report and Literature Review

WANG Jing, WANG Xiao-hui()   

  1. The First School of Clinical Medicine of Lanzhou University, Lanzhou 730000, China (WANG Jing); Department of Obstetrics and Gynecology, The First Hospital of Lanzhou University, Key Laboratory of Gynecological Tumor of Gansu Province, Lanzhou 730000, China (WANG Xiao-hui)
  • Received:2024-03-03 Published:2024-10-15 Online:2024-10-17
  • Contact: WANG Xiao-hui, E-mail: xiaohuiwang2015@163.com

Abstract:

Cervical carcinosarcoma is a malignant tumor composed of malignant epithelial tissue and stromal components. Patients typically present with irregular vaginal bleeding and discharge. The etiology and pathogenesis of this condition remain unclear, and it is clinically very rare, making misdiagnosis and missed diagnosis common. This report presents a case of 42-year-old woman with cervical carcinosarcoma. The patient was admitted to the hospital due to contact bleeding accompanied by lower abdominal pain. Pelvic magnetic resonance imaging revealed a significant enlargement of the cervical region, with an initial diagnosis of cervical tumor. The patient subsequently underwent radical hysterectomy, pelvic lymphadenectomy, and omentectomy. Postoperative pathology confirmed the diagnosis of cervical carcinosarcoma, stage Ⅱb. As of March 2, 2024, the patient had undergone three rounds of chemotherapy, with no evidence of recurrence or metastasis detected so far. Cervical carcinosarcoma is highly malignant with nonspecific clinical manifestations, and definitive diagnosis relies mainly on pathological and immunohistochemical examinations. Therefore, early recognition and treatment are crucial for improving patient prognosis.

Key words: Carcinosarcoma, Uterine cervical neoplasms, Diagnosis, Therapy, Case reports