Abstract:

Spontaneous ovarian hyperstimulation syndrome (sOHSS) mostly occurs in pregnancy, and sOHSS in non-pregnany is extremely rare. Timely diagnosis is difficult due to the lack of ovulation induction history, the usual combination of hydrothorax and ascites in patients with severe and very severe disease, and difficulty in distinguishing the imaging manifestations from ovarian tumors. We report a rare case of severe sOHSS in non-pregnancy, a 20-year-old female who presented to the hospital with coughing, nausea, and vomiting, and was referred to gynecology department for further management after examination revealed bilateral pleural effusions and pelvic masses. Through imaging examinations and laboratory tests, other diseases such as ovarian malignant tumors were excluded, and the diagnosis of sOHSS was confirmed by the combination of irregular menstruation and ovarian imaging manifestations, sOHSS was treated with symptomatic supportive therapy, including intravenous rehydration, correction of anemia, and thoracic drainage, etc., and the patient′s condition gradually improved and she was eventually discharged from the hospital. sOHSS is difficult to diagnose and has a variety of clinical manifestations, so clinicians need to be vigilant about sOHSS when faced with similar symptoms to avoid misdiagnosis and over treatment.

Key words: Spontaneous ovarian hyperstimulation syndrome, Follicle stimulating hormone, Polycystic ovary syndrome, Diagnosis, Case reports