Abstract:

A case of primary undifferentiated uterine sarcoma of the cervix is reported. The patient presented for medical consultation due to vaginal bleeding for 1 week after 7 years of menopause. A 9 cm mass in the cervix was detected during a gynecological examination. Imaging studies indicated a huge cervical mass and pelvic effusion, with no obvious enlarged lymph nodes. Subsequently, an abdominal total hysterectomy and bilateral salpingo-oophorectomy were performed. Postoperative pathological biopsy and immunohistochemistry suggested low-grade undifferentiated uterine sarcoma. After the operation, the patient refused radiotherapy and chemotherapy and did not undergo regular follow-up. Six months later, the patient presented again with vaginal bleeding and lower abdominal distension and pain. Imaging showed a space-occupying lesion at the vaginal stump, and tumor recurrence was considered possible. Therefore, transcatheter internal iliac artery embolization, iliac artery angiography and intra-arterial injection of chemotherapy drugs (cisplatin 60 mg + epirubicin 30 mg) were carried out. Two months later, the patient received chemotherapy once at another hospital due to intermittent vaginal bleeding. The patient was followed up regularly for 9 months, during which no treatment was administered, and intermittent vaginal bleeding occurred. The patient was then lost to follow-up.

Key words: Sarcoma, Uterine cervical neoplasms, Diagnosis, Therapy, Prognosis