Abstract: 【Abstract】Objective: To study relationship of the anti-Mullerian hormone (AMH) and and insulin resistance (IR) in non-obese women with polycystic ovary syndrome (PCOS). Methods: The study enrolled 102 non-obese women with PCOS, in which insulin resistance group (PCOS with IR, n = 48), non-insulin-resistant group (PCOS without IR, n = 54), and the age and body mass index matched 50 non-obese healthy people as a control group. the three groups of c and the relationship between AMH and PCOS with IR. Results: Serum AMH levels and HOMA-IR in PCOS with IR group were significantly higher than PCOS with IR and control group, (p <0.05). Conclusion: Elevated serum AMH levels were found in non-obese PCOS with IR patients, AMH may be associated with PCOS with IR. 【Key words】Polycystic ovary syndrome, anti-Mullerian hormone, insulin resistance