Journal of International Obstetrics and Gynecology ›› 2016, Vol. 43 ›› Issue (4): 424-427.

• 综述 • Previous Articles     Next Articles

The Analysis of Dysregulated miRNAs Involved in Cervical Cancer

QU Jian-hua, CAO Wen-jun, MIAO Cong-xiu   

  1. Changzhi Medical College, Changzhi 046000, Shanxi Province, China
  • Received:1900-01-01 Revised:1900-01-01 Published:2016-08-15 Online:2016-08-15

Abstract: MicroRNAs(miRNAs) have become the center of interest in oncology and are closely associated with a variety of tumors including the occurrence, development, invasion and metastasis of cervical cancer. Great concern has been raised regarding the correlation between cervical cancer and miRNAs. Studies demonstrated that some mechanisms could cause aberrant expressions of miRNAs. MiRNAs regulate gene expression by influencing important regulatory genes and thus are responsible for causing cervical cancer which plays a key role in malignant transformation of cervical cancer. In this paper, the pathogenesis of miRNAs dysregulation in different stages of cervical cancer are reviewed.