Journal of International Obstetrics and Gynecology ›› 2016, Vol. 43 ›› Issue (4): 428-431.

• 综述 • Previous Articles     Next Articles

Clinical Application of Carbon Nanoparticle in Sentinel Lymph Node Detection in Patients with Early Cervical Cancer

WEI Jin-ying,LU Yan,YAO De-sheng   

  1. Department of Gynecologic Oncology, Affiliated Tumor Hospital of Guangxi Medical University, Nanning 530021, China
  • Received:1900-01-01 Revised:1900-01-01 Published:2016-08-15 Online:2016-08-15
  • Contact: YAO De-sheng

Abstract: Whether lymph node metastasis or not is an independently risk factor for the prognosis of patients with early cervical cancer and an evidence for postoperative adjuvant therapy. It is a very low prevalence of lymph node metastasis in early cervical cancer. And most early cervical cancers with pelvic lymph node metastasis don′t benefit from the complete pelvic lymph node dissection. In order to reduce complications, it suggests that tracing sentinel lymph node (SLN) may accurately predict the peivic lymph node,and then the sentinel lymph node biopsy can take place of the complete pelvic lymph node dissection. Although,it has not yet been odopted as a standard of care,the appearing of carbon nanoparticle(CNP) offers an encouraging opportunity. CNP has the feature of tendency of the lymphatic system and chemotherapy adsorption,and then it can gather in lymphatic vessels and lymph nodes with high density and long time,which is a good guide for malignancy surgery and lymphatic chemotherapy.This review will focus on the feasibility of tracing SLN of early stage cervical cancer before surgery by CNP suspension,which provides the possible replacement of the complete pelvic lymph node dissection for the sentinel lymph node biopsy.