Abstract: Congenital laryngeal cyst is one of the causes of neonatal airway obstruction. The incidence of congenital laryngeal cyst ranges from 1.82/100,000 to 3.49/100,000, 50% of which were found in autopsy of asphyxiated children. Lack of awareness of the disease can lead to delays in the condition and even death of newborns. This paper reports 2 cases of congenital laryngeal cyst of newborn delivered by the Characteristic Medical Center of The Chinese People′s Armed Police Force. When newborns suffer from asphyxia of unknown cause, have low Apgar score and poor resuscitation effect after birth, besides obstetric factors, congenital laryngeal cyst to neonatal respiratory obstruction should also be considered. Laryngoscopy is recommended. Cyst puncture and drainage can be used in emergency to reduce the cyst volume in the shortest time and alleviate the critical situation of dyspnea. One step therapy wins the opportunity.

Key words: Infant, newborn, Case reports, Congenital laryngeal cyst